Blog Archives

Immunosuppression: Gefahr der Reaktivierung einer Hepatitis-B-Virus Infektion unter Pomalidomid (Imnovid) Therapie

29. April 2016 – Pomalidomid (Imnovid) ist in Kombination mit Dexamethason indiziert für die Behandlung des rezidivierten und refraktären multiplen Myeloms bei erwachsenen Patienten, die mindestens zwei vorausgegangene Therapien, darunter Lenalidomid (Revlimid) und Bortezomib (Velcade),

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Widerruf der Zulassung fusafunginhaltiger Arzneimittel: Rote-Hand-Brief des BfArM

26. April 2016 – Mittels Rote-Hand-Brief informiert die betroffene Firma, Les Laboratories Servier, die Fachkreise über den Widerruf der Zulassungen von fusafunginhaltiger Arzneimitteln (Locabiosol, angewendet als Mund/Nasenspray) innerhalb der Europäischen Union (EU) gemäss der Mitteilung des Europäischen Ausschusses für Risikobewertung im Bereich der Pharmakovigilanz (PRAC) vom 12.

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Arzneimittel unter zusätzlicher Überwachung: Das schwarze Dreieck

11. Mai 2013 – Diese Mitteilung wurde kürzlich auf dem Pharmakovigilanz-Portal des deutschen Bundesinstitutes für Arzneimittel und Medizinprodukte (BfArM) veröffentlicht und wird hier im unveränderten Wortlaut wiedergegeben. Personen im Gesundheitswesen wie auch Patientinnen/Patienten und deren Angehörige sollten sich diese Veröffentlichung gut ansehen sofern sie Medikamente einnehmen, welche erst kürzlich am Markt eingeführt wurden oder ein neues therapeutisches Wirkungsprinzip beinhalten.

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Efalizumab [Raptiva] Zulassung sistiert

Die Zulassung von Efalizumab [Raptiva] wird in der Schweiz zum 1. Mai 2009 sistiert. Es sollen bis auf weiteres keine neuen Patienten mehr auf Raptiva eingestellt werden.

Raptiva ist ein immunsuppressiv wirksamer, humanisierter monoklonaler Antikörper, der 2004 in der Schweiz zur Behandlung von erwachsenen Patienten mit mittelschwerer bis schwerer Psoriasis vom Plaque-Typ zugelassen wurde.

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  • Study of rare genetic disorder that effects the eyes April 3, 2020
    Nagano prefecture is home to a group of people affected with a rare genetic neurodegenerative disorder called familial amyloid polyneuropathies (FAP). This disease impacts the gene encoding protein transthyretin (TTR) which is produced in the liver and also eyes. Liver transplants are often a treatment for this disease, but severe eyesight problems such as cloudiness […]
  • Natural sunscreen gene influences how we make vitamin D April 2, 2020
    Genetic variations in the skin can create a natural sunscreen, according to University of Queensland researchers investigating the genes linked with vitamin D.
  • Single mutation leads to big effects in autism-related gene April 2, 2020
    A new study in Neuron offers clues to why autism spectrum disorder (ASD) is more common in boys than in girls. National Institutes of Health scientists found that a single amino acid change in the NLGN4 gene, which has been linked to autism symptoms, may drive this difference in some cases. The study was conducted […]
  • Lifestyle changes could delay memory problems in old age, depending on our genes April 2, 2020
    Researchers from King's College London have shown that how we respond to changes in nutrients at a molecular level plays an important role in the aging process, and this is directed by some key genetic mechanisms.
  • Geneticists are bringing personal medicine closer for multiracial individuals April 2, 2020
    A new study in Nature Communications proposes a method to extend polygenic scores, the estimate of genetic risk factors and a cornerstone of the personalized medicine revolution, to individuals with multiple ancestral origins. The study was led by Dr. Davide Marnetto from the Institute of Genomics of the University of Tartu, Estonia and coordinated by […]
  • Study of rare genetic disorder that effects the eyes April 3, 2020
    Small gauge vitrectomy for vitreous amyloidosis and subsequent management of secondary glaucoma in patients with hereditary transthyretin amyloidosis.
  • Tissue dynamics provide clues to human disease April 3, 2020
    Scientists in EMBL Barcelona's Ebisuya group, with collaborators from RIKEN, Kyoto University, and Meijo Hospital in Nagoya, Japan, have studied oscillating patterns of gene expression, coordinated across time and space within a tissue grown in vitro, to explore the molecular causes of a rare human hereditary disease known as spondylocostal dysostosis. Their results are published […]
  • Coronavirus: Virological findings from patients treated in a Munich hospital April 3, 2020
    In early February, research teams from Charité - Universitätsmedizin Berlin, München Klinik Schwabing and the Bundeswehr Institute of Microbiology published initial findings describing the efficient transmission of SARS-CoV-2. The researchers' detailed report on the clinical course and treatment of Germany's first group of COVID-19 patients has now been published in Nature*. Criteria may now be […]
  • Case study: Treating COVID-19 in a patient with multiple myeloma April 3, 2020
    A case study of a patient in Wuhan, China, suggests that the immunosuppressant tocilizumab may be an effective COVID-19 treatment for very ill patients who also have multiple myeloma and other blood cancers. The report, published in Blood Advances, also suggests that blood cancer patients may have atypical COVID-19 symptoms.
  • Indigenous American ancestry may be associated with HER2-positive breast cancer April 3, 2020
    An increased proportion of Indigenous American (IA) ancestry was associated with a greater incidence of HER2-positive breast cancer, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.