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Valproate: Verhindert denn eine Patientenkarte teratogene Schädigungen von Kindern?

14. Juli 2017 – Das deutsche Bundesinstitut für Arzneimittel und  Medizinprodukte (BfArM) hat soeben einen von den betroffenen pharmazeutischen Unternehmen verfassten Informationsbrief zur Einführung einer Patientenkarte für Arzneimittel, welche Valproat (Valproinsäaure) und verwandte Substanzen enthalten, zu Handen der Ärzte und Apotheker veröffentlicht.

Hintergrund dieses Informationsbriefes ist der Bescheid des BfArM vom 10.

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Wer kennt Duogynon (Norethisteron)? Eine dunkle Geschichte

10. Dezember 2016 – Wenn langsam der Winter ins Land zieht und weihnächtliche Romantik selbst in hochprofessionelle Arbeitswelten modernster Ausgestaltung Einzug hält, ertappt sich der Author dieses imageBlogs dabei, nostalgisch zu werden und hie und da geudanklich in die anscheinend bessere Vergangenheit abzuschweifen. Interessanterweise stösst man dabei in den dunklen Monaten nicht selten auch auf eher dunkle Geschichten.

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Teratogenität des Wirkstoffes Acitretin: Ausweitung des Kontrazeptionszeitraumes nach Therapieende auf 3 Jahre

15. September 2016 – Der Wirkstoff Acitretin ist ein Retinoid, welcher zur Behandlung von schweren und schwersten Verhornungsstörungen der Haut (z.B. Psoriasis, Ichthyosis, Lichen ruber planus) in verschiedenen Ländern wie z.B. in Deutschland als Acicutan, in Österreich, Deutschland, und der Schweiz als Neotigason,

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Teratogenes Risiko von Mycophenolat Mofetil -haltigen Arzneimitteln

22 Februar 2016 – Sowohl Swissmedic, das Schweizerische Heilmittel-Institut, wie auch das deutsche Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) haben kürzlich neue Kontraindikationen und wichtige neue Hinweise zu Schwangerschaftstests sowie zur Schwangerschaftsverhütung bei Frauen und Männern für CellCept und für Mycophenolat Mofetil-haltige Arzneimittel im allgemeinen zum teratogenen Risiko von Mycophenolat Mofetil erlassen.

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  • Single-cell RNA sequencing reveals details about individual cells in pancreatic tumors September 30, 2020
    Led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and by HonorHealth Research and Innovation Institute, an international team of researchers have described in detail the individual cells that comprise the pancreatic cancer microenvironment, a critical step in devising new treatment options for patients with this aggressive and difficult-to-treat disease.
  • Study: Neanderthal genes are a liability for COVID patients September 30, 2020
    Scientists say genes that some people have inherited from their Neanderthal ancestors may increase their likelihood of suffering severe forms of COVID-19.
  • Concealed cardiomyopathies revealed in cardiac arrest survivors September 30, 2020
    Centenary Institute researchers have discovered that genetic testing can identify "concealed cardiomyopathies" in nearly a quarter of sudden cardiac arrest (SCA) survivors who seem to have a normal heart.
  • Genetic risk of developing obesity is driven by variants that affect the brain September 29, 2020
    Some people are at higher risk of developing obesity because they possess genetic variants that affect how the brain processes sensory information and regulates feeding and behavior. The findings from scientists at the University of Copenhagen support a growing body of evidence that obesity is a disease whose roots are in the brain.
  • Inflammatory gene provides clue to obesity risk September 29, 2020
    A gene that helps to control inflammation increases the risk of obesity and could be turned off in mice to stop weight gain, a study from The University of Queensland has found.
  • Single-cell RNA sequencing reveals details about individual cells in pancreatic tumors September 30, 2020
    Led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and by HonorHealth Research and Innovation Institute, an international team of researchers have described in detail the individual cells that comprise the pancreatic cancer microenvironment, a critical step in devising new treatment options for patients with this aggressive and difficult-to-treat disease. […]
  • Ocean warming and acidification effects on calcareous phytoplankton communities September 30, 2020
    A new study led by researchers from the Institute of Environmental Science and Technology of the Universitat Autònoma de Barcelona (ICTA-UAB) warns that the negative effects of rapid ocean warming on planktonic communities will be exacerbated by ocean acidification.
  • Videos most effective in communicating with parents about secondhand smoke risks September 30, 2020
    The best way to communicate with parent smokers about the risks of secondhand smoke to their children is to use videos depicting the risks, as well as solutions to reduce those risks.
  • Antipsychotics for treating adult depression linked with higher mortality September 30, 2020
    Rutgers researchers, together with colleagues at Columbia University, have reported an increased mortality risk in adults with depression who initiated augmentation with newer antipsychotic medications compared to a control group that initiated augmentation with a second antidepressant.
  • Is it time to reframe the assisted dying debate? September 30, 2020
    Several articles published by The BMJ today explore the debate around assisted dying, in which, subject to safeguards, terminally ill people who are near to death, suffering, and of sound mind, could ask for drugs that they would take to end their lives.
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