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Individuen dunkler Hautfarbe mit natürlichen blonden Haaren – In der Genetik ist alles möglich

Posted on by by Posted in Allelische Variante, Ethnische Zugehörigkeit, Genetische Prädisposition, Personomik, Thasso Post, Theragenomische Medizin No Comments ↓

8. August 2019 – Blondes Haar ist ein eher seltener menschlicher Phänotyp, der fast ausschließlich in Europa und Ozeanien vorkommt. Die menschliche Pigmentierung variiert innerhalb und zwischen den Populationen erheblich und hängt sowohl von der Exposition gegenüber ultravioletter Strahlung (UV) als auch von der Art und Menge des in Melanozyten und Keratinozyten produzierten Melanins ab.

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Clopidogrel-haltige Arzneimittel (Plavix®, Iscover®): potentielle Wechselwirkungen mit Protonen-Pumpen-Inhibitoren (PPIs)

Posted on by by Posted in Arzneimittelinteraktionen, Behördliche Mitteilung, Personalisierte Medizin, Pharmakogenetik, Thasso Post, Theragenomische Medizin No Comments ↓

6. August 2009 – In einer Mitteilung vom 4. August 2009 bittet das Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) um dringende Beachtung der aktualisierten Warnhinweise und Vorsichtsmaßnahmen in der Fachinformation zu Clopidogrel [Plavix] und Clopidogrel [Iscover]. Zu den Änderungen werden Rote-Hand-Briefe versendet. Hier folgend finden sie den leicht editierten und gekürzten Inhalt des Rote Hand Briefes für Plavix®.

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RSS random genetics

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    The immune system is supposed to protect from external microbial invaders, but sometimes it turns its efforts inward, potentially resulting in autoimmune diseases. In a new study, researchers from Osaka University have discovered how reversible modifications to DNA by certain proteins protect from autoimmune diseases, and conversely, how the absence of these proteins paves the […]
  • Concern following gene therapy adverse events July 2, 2020
    The Editor-in-Chief of Human Gene Therapy, the first journal devoted to the field of gene therapy, and one of the world's leading experts on gene therapy have co-authored a new editorial, Moving Forward After Two Deaths in a Gene Therapy Trial of Myotubular Myopathy, in response to the news of two deaths in a now-halted […]
  • How a mutation on the novel coronavirus has come to dominate the globe July 2, 2020
    Flashback to mid-March: the novel coronavirus had reached San Diego, California. Few people could get tested, and even less was known about how the virus mutated as it spread from person to person.
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    Evaluating the genetic correlations across our phenotypes is of essential importance for understanding disease etiology and other potential causality. A new method—published in the journal Nature Genetics—vastly improves estimates of genetic correlations using established resources from genome-wide association studies.
  • Research team develops technology to improve effectiveness of stem cells in regenerative medicine July 2, 2020
    Stem cells have been holding great promise for regenerative medicine for years. In the last decade, several studies have shown that this type of cell, which in Spanish is called "mother cell" because of its ability to give rise to a variety of different cell types, can be applied in regenerative medicine for diseases such […]

RSS random science

  • Towards lasers powerful enough to investigate a new kind of physics July 3, 2020
    In a paper that made the cover of the journal Applied Physics Letters, an international team of researchers has demonstrated an innovative technique for increasing the intensity of lasers. This approach, based on the compression of light pulses, would make it possible to reach a threshold intensity for a new type of physics that has […]
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    Researchers from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences recently developed a new platform for rapid chiral analysis, producing chromatogram-like output without the need for separation.
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    New research from The University of Queensland has found that women who have hot flushes and night sweats after menopause are 70 per cent more likely to have heart attacks, angina and strokes.
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    Researchers from Osaka University identified the epigenetic proteins Tet2 and Tet3 as key regulators of B cell function. They showed that these proteins suppress B cell function and conversely, that Tet2/Tet3 knockout mice develop a mild form of systemic lupus erythematosus due to hyperactivation of T cells. These findings could help develop a novel treatment […]
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