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Germline whole exome sequencing reveals potential role of hereditary predisposition in small cell lung cancer January 27, 2021
A study presented today by Dr. Nobuyuki Takahashi of the Center for Cancer Research (CCR), National Cancer Institute (NCI), Bethesda, Md. at the IASLC World Conference on Lung Cancer Singapore demonstrates that small cell lung cancer (SCLC) may have an inherited predisposition and lays the foundation for understanding the interaction between genotype and tobacco exposure […]
Researchers identify genetic dependencies in tumors that have undergone whole genome doubling January 27, 2021
Researchers from Boston University School of Medicine (BUSM) have identified proteins that are essential for the viability of whole genome doubled tumor cells, yet non-essential to normal cells that comprise the majority of human tissue.
Genetic changes in tumours could help predict if patients will respond to immunotherapy January 27, 2021
Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumors which could be used to predict if immunotherapy drugs would be effective in individual patients.
Epigenetic mechanisms that regulate macrophage inflammation discovered January 27, 2021
How do cis-regulatory genome elements regulate gene expression, what are the critical components involved, and can we therapeutically target them? By investigating how corepressors modulate enhancers and silencers during inflammatory macrophage activation, BioNut researchers have found some unexpected answers to these fundamental questions. The study is published today in Molecular Cell.
Partners in crime: Genetic collaborator may influence severity of the rare disease, NGLY1 January 27, 2021
In 2012, four-year-old Bertrand Might became the first-ever patient diagnosed with a rare genetic disorder called N-glycanase (NGLY1) deficiency. The discovery of this condition and Bertrand's diagnosis allowed doctors to look for other children with the same genetic defect. Since then, more than 60 additional patients have been found. The disease affects every system of […]

20urbain05 on Cannabis als Medizin: Das BfArM richtet Cannabisagentur ein: “Die Cannabis-Agentur des BfArM hat 79 Angebote (Bieter) erhalten zum künftigen Anbau des Cannabis zu medizinischen Zwecken in Deutschland. Siehe…” Feb 3, 12:27
thassodotcom on Die Pille: Erhöhen gewisse Kontrazeptiva das Risiko für potenziell lebensbedrohende VTEs?: “Neben VTE’s gibt es natürlich viel andere Risiken, welche mit hormonellen Kontrazeptiva daherkommen, und oft einfach vergessen oder unterdrückt werden.…” Jan 27, 08:08
Menlo-50 on Auch in der Schweiz: Valsartan ohne Ende: “Wie nicht anders zu erwarten war, werden die krebserregenden Verunreinigungen auch in Sartanen, welche in Europa auf dem Markt sind,…” Jan 27, 06:36
adegas99 on Auch in der Schweiz: Valsartan ohne Ende: “Sehen Sie hier: https://www.fda.gov/Safety/Recalls/ucm629693.htm?utm_campaign=Losartan%20Potassium%20Tablets%2C%20USP%20and%20Losartan%20Potassium%20and%20Hydrochlorothiazide%20Tablets%2C%20USP&utm_medium=email&utm_source=Eloqua Vielleicht muss auch Swissmedic ihre Sartane nochmals untersuchen? Nachdem Verunreinigungen in Valsartan überall auf der Welt…” Jan 24, 05:52
20justin03 on Auch in der Schweiz: Valsartan ohne Ende: “Das Verunreinigungsschicksal holt nun, entgegen den Untersuchungen durch Swissmedic, wohl auch Irbesartan ein: Sehen Sie die Mitteilung der American Food…” Jan 19, 06:06