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Unbekannt oder ein Tabu über das man nicht spricht: Das Post-Finasterid Syndrom

Posted on by by Posted in Gravierende Unerwünschte Nebenwirkung, Thasso Post, Theragenomische Medizin No Comments ↓

13. Novemberr 2016 – Das Post-Finasterid Syndrom (PFS) beschreibt einen von Ärzten, Patienten und Medien verwendeten Begriff für einen Symptomkomplex mit anhaltenden sexuellen, neurologischen, mentalen und körperlichen Nebenwirkungen bei Patienten, die glatze-iiFinasterid, einen 5-alpha-Reduktase-Hemmer zur Behandlung von Haarausfall (androgene Alopezie) unter dem Markennamen Propecia oder Generika) oder einer vergrößerten Prostata (BPH) (unter dem Markenname Proscar oder Generika) eingenommen haben.

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Schlafstörungen, Gedächtnisverlust, sexuelle Dysfunktion, Depression und interstitielle Pneumopathie als mögliche Klasseneffekte von Arzneimitteln, welche die HMG CoA-Reduktase Inhibitoren Atorvastatin, Pravastatin, Fluvastatin, Simvastatin, Lovastatin, und Rosuvastatin als pharmakologisch aktive Wirkstoffe enthalten

Posted on by by Posted in Behördliche Mitteilung, Gravierende Unerwünschte Nebenwirkung, Thasso Post, Theragenomische Medizin No Comments ↓

2. Mai, 2010 – Gemäss einer kürzlichen Mitteilung vom 6. April 2010 hält es das Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) für erforderlich, die Produktinformationen aller HMG-CoA Reduktase-Inhibitoren (Statine: Atorvastatin, Pravastatin, Fluvastatin, Simvastatin, Lovastatin, Rosuvastatin) mit Hinweisen hinsichtlich der Risiken von Schlafstörungen, Gedächtnisverlust, sexueller Störungen, Depression und interstitieller Pneumopathie als möglichen Klasseneffekten zu ergänzen.

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Einheitliche Warnhinweise zum erhöhten Risiko für suizidales Verhalten bei jungen Erwachsenen

Posted on by by Posted in Behördliche Mitteilung, Thasso Post, Theragenomische Medizin, Unerwünschte Arzneimittel Nebenwirkungen No Comments ↓

Im Bestreben, die betroffenen Patienten angemessen auf die Gefahren von Arzneimitteln und deren unerwünschten Nebenwirkungen aufmerksam zu machen, verpflichtet das BfArM pharmazeutische Unternehmen, welche Arzneimittel zur Behandlung von Depression in jungen Erwachsenen auf dem Markt haben, die Warnhinweise und Vorsichtsmassnahmen in den Fachinformationen bei Anwendung Suizid/Suizidgedanken oder klinische Verschlechterung per 1.

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Eine Hoffnung weniger für übergewichtige Patienten: Sistierung der Zulassung von Rimonabant [Acomplia]

Posted on by by Posted in Behördliche Mitteilung, Gravierende Unerwünschte Nebenwirkung, Marktrückzug, Thasso Post, Theragenomische Medizin No Comments ↓

Aufgrund eines Entscheids des Ausschusses für Humanarzneimittel (CHMP) der 
Europäischen Arzneimittelagentur EMA wurde die Zulassung von Rimonabant [Acomplia] in der europäischen 
Union ab 23. Oktober 2008 bis auf weiteres sistiert. In der Folge wurde die Zulassung von Rimonabant [Acomplia] auch in der Schweiz sistiert.  Rimonabant [Acomplia] war in der Schweiz seit März 2007 zugelassen als Zusatztherapie zu einer leicht hypokalorischen Diät und zu einer Bewegungstherapie für die Behandlung von adiposen Patienten (BMI  >

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RSS random genetics

  • Mapping genetic variants driving toxicity to leukemia therapy February 25, 2020
    Scientists at St. Jude Children's Research Hospital, alongside collaborators around the world, have created a comprehensive reference of functional variants in an important drug-metabolizing enzyme called NUDT15. This thorough understanding of NUDT15 variants provides an invaluable resource for predicting which patients being treated with thiopurine drugs for acute lymphoblastic leukemia (ALL) are likely to experience […]
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RSS random science

  • Regular walnut consumption linked to health and longevity in women, according to new study February 25, 2020
    According to a new epidemiological study, women in their late 50s and early 60s who consumed at least two servings of walnuts per week had a greater likelihood of healthy aging compared to those who did not eat walnuts. After accounting for various factors that could impact health in older adults, such as education and […]
  • Cynicism and disrespect: A vicious cycle February 25, 2020
    An international study with data from Europe and the USA has found that disrespectful treatment leads to cynical beliefs about human nature. These cynical beliefs, in turn, again lead to disrespectful treatment.
  • New study shows significant increase in weight after breast cancer February 25, 2020
    New study findings suggest that weight gain after breast cancer is a greater problem than previously thought. The first national survey on weight after breast cancer in Australia, published in BMC Cancer journal, found close to two-thirds (63.7%) of women reported weight gain at an average of nine kilograms after a breast cancer diagnosis, and […]
  • Study finds gender disparities in hematology research success February 25, 2020
    Hematologists who complete a mentored training program experience greater levels of academic success than those who do not; however, a study published today in Blood Advances suggests a slight discrepancy in success levels between male and female hematologists.
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    An international team of researchers led by Associate Professor Daniel Friess and Dr Erik Yando of the National University of Singapore has found that globally, mangrove loss rates have reduced by almost an order of magnitude between the late 20th and early 21st century -- from what was previously estimated at one to three per […]
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