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Les en-têtes de football pourraient être plus risqués pour les porteurs du génotype APOE4

02 février 2020 – Les en-têtes de football pourraient être plus risqués pour les porteurs du génotype APOE4 – c’est le titre d’un récent article de Reuters Health dans Medscape. Par conséquent, les joueurs de football avec le génotype de l’apolipoprotéine E4 (APOE4) devraient être en mesure de limiter le nombre d’en-têtes,

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Les individus de peau foncée aux cheveux blonds naturels – En génétique, tout est possible

8 août 2019 – Les cheveux blonds sont un phénotype humain plutôt rare, présent presque exclusivement en Europe et en Océanie. La pigmentation humaine varie considérablement au sein des populations et entre les populations et dépend de l’exposition aux rayons ultraviolets (UV) ainsi que du type et de la quantité de mélanine produit dans les mélanocytes et les kératinocytes.

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Aspects génétiques de la globésité: Glocalisés oui ou non?

juin 26, 2019 – L’épidémie mondiale d’obésité est si importante qu’elle a maintenant un nom prépondérant: la globésité (qui découle évidemment de l’obésité globale). Des questions très intéressantes se posent dans ce contexte, à savoir s’il existe des facteurs glocalisés (globaux ou locaux) impliqués dans cette épidémie.

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  • Mapping genetic variants driving toxicity to leukemia therapy février 25, 2020
    Scientists at St. Jude Children's Research Hospital, alongside collaborators around the world, have created a comprehensive reference of functional variants in an important drug-metabolizing enzyme called NUDT15. This thorough understanding of NUDT15 variants provides an invaluable resource for predicting which patients being treated with thiopurine drugs for acute lymphoblastic leukemia (ALL) are likely to experience […]
  • Releasing brakes: Potential new methods for Duchenne muscular dystrophy therapies février 24, 2020
    Researchers identified a group of small molecules that may open the door to developing new therapies for Duchenne muscular dystrophy (DMD), an as-yet-uncured disease that results in devastating muscle weakening and loss. The molecules tested by the team from the Perelman School of Medicine at the University of Pennsylvania eased repression of a specific gene, […]
  • Extra chromosomes in cancers can be good or bad février 24, 2020
    Cancer cells are notorious for their genetic disarray. A tumor cell can contain an abundance of DNA mutations and most have the wrong number of chromosomes. A missing or extra copy of a single chromosome creates an imbalance called aneuploidy, which can skew the activity of hundreds or thousands of genes. As cancer progresses, so […]
  • Researchers show that DNA topological problems may cause lymphoma février 24, 2020
    Researchers from the Spanish National Cancer Research Centre (CNIO), Madrid, and the Andalusian Molecular Biology and Regenerative Medicine Centre (Cabimer), Seville, published a paper in Nature Communications that shows that DNA topological problems may cause endogenous DNA breaks that have a causal relationship with cancer.
  • New DNA test that reveals a child's 'true age' has promise, but ethical pitfalls février 24, 2020
    Epigenetic clocks are a new type of biological test currently capturing the attention of the scientific community, private companies and governmental agencies because of their potential to reveal an individual's "true" age.
  • Regular walnut consumption linked to health and longevity in women, according to new study février 25, 2020
    According to a new epidemiological study, women in their late 50s and early 60s who consumed at least two servings of walnuts per week had a greater likelihood of healthy aging compared to those who did not eat walnuts. After accounting for various factors that could impact health in older adults, such as education and […]
  • Cynicism and disrespect: A vicious cycle février 25, 2020
    An international study with data from Europe and the USA has found that disrespectful treatment leads to cynical beliefs about human nature. These cynical beliefs, in turn, again lead to disrespectful treatment.
  • New study shows significant increase in weight after breast cancer février 25, 2020
    New study findings suggest that weight gain after breast cancer is a greater problem than previously thought. The first national survey on weight after breast cancer in Australia, published in BMC Cancer journal, found close to two-thirds (63.7%) of women reported weight gain at an average of nine kilograms after a breast cancer diagnosis, and […]
  • Study finds gender disparities in hematology research success février 25, 2020
    Hematologists who complete a mentored training program experience greater levels of academic success than those who do not; however, a study published today in Blood Advances suggests a slight discrepancy in success levels between male and female hematologists.
  • NUS-led study suggests mangrove forests provide cause for conservation optimism, for now février 25, 2020
    An international team of researchers led by Associate Professor Daniel Friess and Dr Erik Yando of the National University of Singapore has found that globally, mangrove loss rates have reduced by almost an order of magnitude between the late 20th and early 21st century -- from what was previously estimated at one to three per […]