the glocalized network in theragenomic and personalized medicine and the genetics of individual patients safety of drugs
Last Updated on November 5, 2019 by Joseph Gut – thasso November 03, 2019 – Cystic fibrosis (CF) is a lethal, inherited genetic disease affecting more than 70,000 people worldwide. It is usually diagnosed in childhood and causes abnormal buildup …
In Caribbeans cystic fibrosis (CF) is driven by very rare CFTR mutations Read more »
Last Updated on November 2, 2019 by Joseph Gut – thasso November 02, 2019 – Is laziness a choice or genetic trait? At the age where genetics seems to explain everything, it is certainly interessant to learn that a seemingly …
Is laziness a personal choice or a genetic trait? Read more »
Last Updated on October 29, 2019 by Joseph Gut – thasso October 27, 2019 – Genetic tests sold online and in shops are en vogue. More and more patients strive for it, and they (the patients) are getting back results. …
After an over the counter genetic test: Would you make serious health decisions? Read more »
Last Updated on October 30, 2019 by Joseph Gut – thasso October 20, 2019 – Sequencing African genomes yields new data resource with broad applicability. By collaborating globally in a new, large-scale effort, researchers have made strong progress in sequencing …
Hidden secrets in African genomes revealed by large scale sequencing Read more »
Last Updated on September 18, 2019 by Joseph Gut – thasso September 18, 2019 – This post is an edited version of parts of a paper that appeared in the Journal of Personalised Medicine (JPM) a week ago und which addresses …
Clinical evidence and implementation challenges for pharmacogenomic testing Read more »
Last Updated on September 6, 2019 by Joseph Gut – thasso September 06, 2019 – Wakefulness varies largely among human individuals. Barring individuals suffering from diseases such as narcolepsy that may heavily dictate an individual’s daily sleep and wakefulness pattern, there …
Staying wakeful for the day: A second short sleep gene identified Read more »
Last Updated on September 5, 2019 by Joseph Gut – thasso September 05, 2019 – An E-cigarette is a handheld battery-powered vaporizer that simulates smoking by providing some of the behavioral aspects of smoking, including the hand-to-mouth action of smoking, but …
FDA safety communication concerning E-cigarettes Read more »
Last Updated on August 28, 2019 by Joseph Gut – thasso August 28, 2019 – Immune checkpoint inhibitor (ICI) therapy is a form of cancer immunotherapy. The therapy targets immune checkpoints, key regulators of the immune system that when stimulated …
Variables of prospective response rates of PD-1/PD-L1 based therapies across cancers Read more »
Last Updated on August 23, 2019 by Joseph Gut – thasso August 23, 2019 – Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal viral disease characterized by progressive damage or inflammation of the white matter of the brain at multiple …
Therapies that promote progressive multifocal leukoencephalopathy (PML) Read more »
Last Updated on August 13, 2019 by Joseph Gut – thasso August 13, 2019 – Onasemnogene abeparvovec-xioi (Zolgensma) is an adeno-associated virus vector-based gene therapy indicated for the treatment of pediatric patients less than 2 years of age with spinal muscular …
Onasemnogene abeparvovec-xioi (Zolgensma): Approval strategy with manipulated data? Read more »