March 30, 2025 – A new study from Queen Mary University of London found that 9% of all reported adverse drug reactions (ADRs) reported to the UK medicines regulator are associated with medications where side effect risk is partly dependent …
December 30, 2024 – Transthyretin cardiac amyloidosis (TTR-CA) is now increasingly becoming recognized as an important cause of heart failure, and some studies have shown that as much as a third of diastolic heart failure could be attributed to TTR-CA. …
Uneven burden of cardiac amyloidosis in people of African descent Read more »
December 15 2024 – Eighty-seven years after launching the National Cancer Act in the United Stated with the intention of a national combat against cancer, and despite despite significant progress, cancer treatment often falls short, with 50% to 80% of …
Predictive Score: Genetics behind anti-cancer drug resistance Read more »
03 January 2024 – 23andMe is a personal genomics company out of South San Francisco, It is best known for providing a direct-to-consumer (DTC) genetic testing service in which customers provide a saliva sample that is laboratory analysed, using single nucleotide polymorphism …
November 25, 2023 – Sickle cell anemia is an inherited disease of red blood cells (erythrocytes). It belongs to the group of hemoglobinopathies (hemoglobin disorders) and leads to corpuscular hemolytic anemia. Affected people have a mutation in the hemoglobin β …
Sickle cell anemia: Genetic scissors drug approved for first time Read more »
August 04, 2023 – We at thasso recently had an article (blog) on the much discussed and recently throughout the social media as wonder compound (drug) for weight loss promoted active ingredient Semaglutide in the form of the newly marketed product …
Is there living pharmacogenovigilance behind Semaglutide drugs? Read more »
01 May, 2023 – SARS-CoV-2, like other respiratory viruses, typically initiates infection in the throat and sinuses. But it often spreads from the respiratory tract to other parts of the body, such as the gut, liver, heart, kidneys, brain, blood …
Study identifies human genes enabling SARS-CoV-2 infection Read more »
March 01, 2023 – The gene APOE codes for apolipoprotein E (Apo-E), a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in the Alzheimer’s disease and cardiovascular diseases. Recently, researchers at Stanford University …
APOE Missense Variant Linked to Increased Alzheimer’s Disease Risk in African Americans Read more »
January 08, 2023 – In precision and/or targeted medicine of today, physicians typically start out with the determination of the patients phenotypic expression of a disease (i.e., establish a clinical finding) and then go on into finding out the patients genetic …
Genomic variants traced forward to genetic disorders: A new approach? Read more »
November 20, 2022 – The genetics of drug side-effects. Some 95% of people have a gene variant that affects their response to at least one drug. Treating physicians, clinical researchers, and affected patients know all to well the serious problems that …
Is there pre-emptive genotyping to avoid adverse drug effects (ADRs)? Read more »