November 20, 2022 – The genetics of drug side-effects. Some 95% of people have a gene variant that affects their response to at least one drug. Treating physicians, clinical researchers, and affected patients know all to well the serious problems that …

Is there pre-emptive genotyping to avoid adverse drug effects (ADRs)? Read more »

September 25, 2022 – Nearly 2000 years ago the Roman scholar and natural philosopher Pliny the Elder wrote in his Natural History: “Ex Africa surgit semper aliquid novi” (from Africa there is always something new). This quote beautifully applies to …

Genetic studies of African populations on disease susceptibility and response to vaccines and therapeutics  Read more »

September 21, 2022 – Here, a big bias in genetic research into its applicability on “personalized”, or “precision”, or “theragenomic” medicine is finally addressed and brought forward to all involved in these fields. The problem until now is (and was} that …

Ethnic equity in precision medicine Read more »

13 June 2022 – Sometimes, patients genetics can be bewildering and/or unjust. Common belief with patients and the general public would be that genetic variants would be responsible for causing all kinds of adverse drug reactions (ADR’s) and be at the …

Rare APOE genetic variants reduce Alzheimer’s risk Read more »

09 June 2022 – The individium in general and the patient in the context discussed here, are the phenotype experts on their forms of proper disease they are suffering from. It is not their treating physician, it is not a …

Just a reminder: Thasso and the apomediary patient Read more »

April 30, 2022 – In a very recent report published in PLoS Genetics  by Dr. Verma of the Corporal Michael Crescenz VA Medical Center in Philadelphia, Pennsylvania, US, and colleagues, new data from the Veterans Affairs Million Veteran Program (MVP) has …

Genetic links revealed between severe COVID-19 and other diseases Read more »

April 10, 2022 – Sotrovimab, sold under the brand name Xevudy, is a monoclonal antibody that was available under emergency use authorization (EUA) from the FDA and similar urgency authorisations from several drug regulatory agencies worldwide for the treatment of patients …

SARS-CoV-2 Delta Variant: Resistance Mutations after Sotrovimab Use Read more »

October 28 , 2021 – One of the most interessant and still unresolved question in connection with Covid-19 disease is the fact that some patients develop a heavy, if not fatal forms of Covid-19 disease after their infection with SARS-CoV-2 while …

Drivers of severe Covid-19 disease in patients under 50 without comorbidities Read more »

July 14, 2021 – Why does a SARS-CoV-2 infection make some people so sick with Covid-19 disease? And why do some infected people barely fall ill if at all? The answer may be that you have to talk to their …

Genetic susceptibility and severity loci for Covid-19 disease Read more »

March 28, 2021 – Recent reports from the United Kingdom (UK) and from throughout the European Union (EU) have suggested that the SARS-CoV-2 (Covid-19) vaccine made by AstraZeneca was at the origin of the development of a very rare type …

Covid-19 Vaccines: Is there genetic predisposition for thrombosis? Read more »