Blog Archives

In Caribbeans cystic fibrosis (CF) is driven by very rare CFTR mutations

Read more ›

Tags: , , , , , , , , ,

Clinical evidence and implementation challenges for pharmacogenomic testing

September 18, 2019 – This post is an edited version of parts of a paper that appeared in the Journal of Personalised Medicine (JPM) a week ago und which addresses one of the important topics in connection with the themes of personalised medicine,

Read more ›

Tags: , , , , , , , , , , , , , , , ,

Variables of prospective response rates of PD-1/PD-L1 based therapies across cancers

August 28, 2019 – Immune checkpoint inhibitor (ICI) therapy is a form of cancer immunotherapy. The therapy targets immune checkpoints, key regulators of the immune system that when stimulated can dampen the immune response to an immunologic stimulus.

Read more ›

Tags: , , , , , , , , , , , , , , ,

ZRANB3 in African Populations: New Type 2 Diabetes risk locus identified

August 03, 2019 – Africa is considered the original cradle of all humanity, to which all humans can trace their genetic origin. This may be very interesting in the context of diseases that are due to genetic predispositions both in todays African populations and in all the populations descendant of African origin worldwide.

Read more ›

Tags: , , , , , , , ,

The phenotype broker: Blockchain and patient phenotype

July 26, 2019 – “Blockchains for secure digitized medicine”. This is the title of a very interesting and important article in the Journal of Personalised Medine (JPM) as of May 28, 2019.

Blockchain as an emerging technology (particularly around the hype on Bitcoins) has been gaining in popularity,

Read more ›

Tags: , , , , , , , , , , , , , , , , ,

Status of genetics behind male infertility

In recent years,

Read more ›

Tags: , , , , , , , , , , ,

Gene therapy: Zolgensma to treat spinal muscular atrophy

May 29, 2019 – Spinal muscular atrophy (SMA) is a group of neuromuscular disorders that result in the loss of motor neurons and progressive muscle wasting. The severity of symptoms and age of onset varies by the type. Some types are apparent at or before birth while others are not apparent until adulthood. 

Read more ›

Tags: , , , , , , , , , ,

Cholangiocarcinoma: Diabetes Drugs In DPP-4 Inhibitor Class Associated With Doubled Risk

Read more ›

Tags: , , , , , , , , , , , , , , , , , , , , ,

CRISPR/Cas9 for the Treatment of Duchenne Muscular Dystrophy: Prime time already?

December 12, 2018 – The application of CRISPR/Cas9 based molecular technology in the field of gene editing (or genome editing) has recently had its exploded limelight exposure for a couple of reasons. The question arises if this exposure is earned or somewhat premature.

Read more ›

Tags: , , , , , , , , , , , , , , , ,

Living theragenomic medicine: Direct to consumer test for metabolism of drugs FDA approved

November 08, 2018 –  The American Food and Drug Administration (FDA) has just authorized the first direct-to-consumer test for detecting genetic variants in genes that may govern the metabolism of drugs in individual patients.

Thus, FDA permits marketing, with special controls,

Read more ›

Tags: , , , , , , , , , , , , , , , ,

thasso: conditions

thasso: tweets

thasso post: magazine

View my Flipboard Magazine.

thasso: categories

thasso: archives

thasso: simple chat

You must be a registered user to participate in this chat.

  • Avatar worms help to identify factors that modify genetic diseases January 21, 2020
    Often, patients from the same family and carriers of the same genetic mutation, develop a disease differently. This disparity may be due to the existence of mutations in other secondary genes, which influence the onset and progression of the disease caused by the main mutation. As an example, members of a family who are carriers […]
  • Algorithm turns cancer gene discovery on its head January 21, 2020
    A method for finding genes that spur tumor growth takes advantage of machine learning algorithms to sift through reams of molecular data collected from studies of cancer cell lines, mouse models and human patients.
  • Blood test for eight gene signatures could predict onset of tuberculosis January 21, 2020
    Scientists at UCL have shown a blood test could predict the onset of tuberculosis three to six months before people become unwell, a finding which could help better target antibiotics and save countless lives.
  • Scientists develop test that will help prevent glaucoma-related blindness January 21, 2020
    Australian researchers have identified 107 genes that increase a person's risk of developing the eye disease glaucoma, and developed a genetic test to detect those at risk of going blind from it.
  • Drug profiling and gene scissors open new avenues in immunotherapy January 21, 2020
    Researchers have discovered ways to boost CAR T-cell therapy. According to a study published in the Blood journal, drug profiling and the CRISPR-Cas9 gene editing method have opened new avenues in the development of CAR T-cell therapy, used to treat leukemia and lymphoma.
Top