Last Updated on February 2, 2019 by Joseph Gut – thasso February 02, 2019 –  This is potential alarming news for millions of patients worldwide suffering from high blood pressure: Health Canada has just completed a safety review of hydrochlorothiazide and …

Hydrochlorothiazide and non-melanoma skin cancer: How come? Read more »

Last Updated on July 10, 2019 by Joseph Gut – thasso January 26, 2019 – Pharmacogenomic approaches are increasingly revealing newly identified genes and genetic variants that are at the base of remarkable inter-individual pharmacokinetic and pharmacodynamic variation of novel direct oral …

Direct Oral Anticoagulants (DOAC): Newly Identified Genes and Genetic Variants Read more »

Last Updated on January 19, 2019 by Joseph Gut – thasso January 21, 2019 – Stuff to Read: As the Y chromosome is disappearing, we prepare ourselves to say goodbye to men, while asking if we could, and/or should, engineer animals …

Stuff to read: Why should our Y chromosome disappear, after all? Read more »

Last Updated on May 16, 2019 by Joseph Gut – thasso January 16, 2109 – Despite drug safety problems of cardiovascular mortality with Febuxostat (Uloric), the benefits might still be seen to outweigh risks for selected gout patients. This notion …

Febuxostat (Uloric) and its problem with cardiovascular mortality Read more »

Last Updated on January 16, 2019 by Joseph Gut – thasso January 15, 2019 – The World Health Organization (WHO) classifies combined hormonal contraception as an unacceptable health risk in the presence of a known thrombogenic mutation but advises against …

Combined hormonal contraception: Is there an unacceptable health risk? Read more »

Last Updated on January 15, 2019 by Joseph Gut – thasso January 13, 2019 – Are genetic variations in the sweet taste receptor gene related to chocolate powder and dietary fiber intake in obese children and adolescents? This was the …

Sweet taste receptor gene TAS1R2 and chocolate powder Read more »

Last Updated on January 12, 2019 by Joseph Gut – thasso January 12, 2018 – Fabry disease is an inherited disorder caused by mutations (alterations) in the alpha-galactosidase A (GLA) gene located on the X-chromosome. Fabry disease is rare and affects …

Migalastat (Galafold): New treatment for Fabry disease Read more »

Last Updated on January 15, 2019 by Joseph Gut – thasso January 09, 2019 – Women should be alerted: Is there a thing like breast implant associated cancer (BIA-ALCL)? Yes, there is. Not every woman with a breast implant will get …

Is there breast implant-associated cancer (BIA-ALCL)? Read more »

Last Updated on November 8, 2019 by Joseph Gut – thasso January 08, 2019 – The interpretation of genetic variants after genome-wide analysis is complex in a selection of heterogeneous disorders which are at the base of a condition termed …

You cannot hide it: Your face tells all about your ID Read more »