Last Updated on August 13, 2019 by Joseph Gut – thasso August 13, 2019 – A very significant research article by the title “Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing” has just appeared in the …

Cystic fibrosis: CFTR-gene editing may cure this genetic disease Read more »

Last Updated on August 8, 2019 by Joseph Gut – thasso August 07, 2019 – Blonde hair is a rare human phenotype found almost exclusively in Europe and Oceania. Human pigmentation varies considerably within and among populations and is a …

Black people with natural blonde hair – Everything is possible in genetics Read more »

Last Updated on August 4, 2019 by Joseph Gut – thasso August 03, 2019 – Africa is considered the original cradle of all humanity, to which all humans can trace their genetic origin. This may be very interesting in the …

ZRANB3 in African Populations: New Type 2 Diabetes risk locus identified Read more »

Last Updated on August 1, 2019 by Joseph Gut – thasso August 01, 2019 – Post-Traumatic Stress Disorder (PTSD) is a mental disorder that can develop after a person is exposed to a traumatic event, such as sexual assault, warfare, traffic …

Risk loci for post-traumatic stress disorder (PTSD) Read more »

Last Updated on March 15, 2020 by Joseph Gut – thasso July 26, 2019 – “Blockchains for secure digitized medicine”. This is the title of a very interesting and important article in the Journal of Personalised Medine (JPM) as of May …

The phenotype broker: Blockchain and patient phenotype Read more »

Last Updated on June 27, 2019 by Joseph Gut – thasso June 25, 2019 – The global obesity epidemic is so far-reaching it now has an overarching name: globesity (obviously derived from global obesity).  Very interesting questions arise in this …

Genetic aspects of globesity: Glocalized or not? Read more »

Last Updated on June 23, 2019 by Joseph Gut – thasso June 20, 2019 – Male infertility is a serious treat in very many relations. While a priori, male infertility does not affect the physical health of the afflicted, it may …

Status of genetics behind male infertility Read more »

Last Updated on June 13, 2019 by Joseph Gut – thasso June 13, 2019 – This is simply fascinating stuff. Researchers are testing neural networks that automatically combine portrait photos with genetic and phenotypic patient data in order to obtain definitive …

Where portrait photos meet genetics and AI Read more »

Last Updated on June 11, 2019 by Joseph Gut – thasso June 08, 2019 – For some time now, Tofacitinib (Xeljanz) receives intense attention in the media, with regulatory authorities, and patients and treating physicians alike because of serious concerns of increased risk …

Tofacitinib (Xeljanz): Dangers of blood clots in the lungs and of death Read more »

Last Updated on May 30, 2019 by Joseph Gut – thasso May 30, 2019 – The American Food and Drug Administration (FDA) recently approved Alpelisib (Piqray) to be used in combination with the FDA-approved endocrine therapy fulvestrant, to treat postmenopausal women, …

The PI3K inhibitor Alpelisib (Piqray) for progressing breast cancer in women (and men) Read more »