the glocalized network in theragenomic and personalized medicine and the genetics of individual patients safety of drugs
November 25, 2023 – Sickle cell anemia is an inherited disease of red blood cells (erythrocytes). It belongs to the group of hemoglobinopathies (hemoglobin disorders) and leads to corpuscular hemolytic anemia. Affected people have a mutation in the hemoglobin β …
Sickle cell anemia: Genetic scissors drug approved for first time Read more »
August 04, 2023 – We at thasso recently had an article (blog) on the much discussed and recently throughout the social media as wonder compound (drug) for weight loss promoted active ingredient Semaglutide in the form of the newly marketed product …
Is there living pharmacogenovigilance behind Semaglutide drugs? Read more »
01 May, 2023 – SARS-CoV-2, like other respiratory viruses, typically initiates infection in the throat and sinuses. But it often spreads from the respiratory tract to other parts of the body, such as the gut, liver, heart, kidneys, brain, blood …
Study identifies human genes enabling SARS-CoV-2 infection Read more »
January 08, 2023 – In precision and/or targeted medicine of today, physicians typically start out with the determination of the patients phenotypic expression of a disease (i.e., establish a clinical finding) and then go on into finding out the patients genetic …
Genomic variants traced forward to genetic disorders: A new approach? Read more »
November 20, 2022 – The genetics of drug side-effects. Some 95% of people have a gene variant that affects their response to at least one drug. Treating physicians, clinical researchers, and affected patients know all to well the serious problems that …
Is there pre-emptive genotyping to avoid adverse drug effects (ADRs)? Read more »
September 25, 2022 – Nearly 2000 years ago the Roman scholar and natural philosopher Pliny the Elder wrote in his Natural History: “Ex Africa surgit semper aliquid novi” (from Africa there is always something new). This quote beautifully applies to …
August 26, 2022 – Traditionally, pharmacovigilance (PV), is the pharmaceutical science relating to the “collection, detection, assessment, monitoring, and prevention” of adverse drug reactions (ADRs) with pharmaceutical products and associated therapies. Pharmacovigilance is based on information about ADRs received from patients and healthcare …
August 21, 2022 – Systemic lupus erythematosus (SLE) is a common, incurable autoimmune disease that affects millions of individuals worldwide, with a particularly high prevalence among women. A genetic variant, called HLA-DRB1*03:01, is the greatest risk factor for the condition, …
Serious lupus: Strong genetic risk factor on its path Read more »
August 18, 2022 – The question why certain patients suffer from very severe, even fatal conditions after infections with SARS-CoV-2 has occupied patients, the general population, medical professionals, and the media all alike for some time now. As a basic researcher …
Do genomic regions influence the severity of Covid-19 disease? Read more »
29 July 2022 – This is a mind-boggling article out of the MedicalXpress news portal, which I present here almost original and unedided. So, all the credentials go to the authors at MedicalXpress. Here the article: The Rady Children’s Institute for …
Is there rapid management of 500 (rare) genetic diseases? Read more »