July 14, 2021 – Why does a SARS-CoV-2 infection make some people so sick with Covid-19 disease? Ans why doe some infected people barely fall ill if at all? The answer may be that you have to talk to their …

Genetic susceptibility and severity loci for Covid-19 disease Read more »

January 30, 2021 – The COVID-19 pandemic has caused considerable morbidity and mortality, and has resulted in the death of over a million people to date. The clinical manifestations of Covid-19 disease, caused by its underlying virus SARS-CoV-2, vary widely in …

Strong evidence of genetic predisposition for COVID-19 disease Read more »

December 28, 2020 – Some 95% of people have gene variants that may negatively affect their response to at least one drug, leading to unexpected or adverse drug reactions (ADRs) or, if unlucky, to a serious, if not fatal, adverse …

Genetics behind some serious adverse drug reactions (SADRs) Read more »

October 15, 2020 – SARS-CoV-2 and its resulting disease, Covid-19 disease, is (still) rattling the world. It still remains largely unknown, at this point in time, which are the infected individuals who fall very seriously, even fatally, ill with Covid-19 disease. …

Gene variants tied to increased risk of severe COVID-19 disease Read more »

June 13, 2020 – To help disentangle the secrets of Covid-19 disease, researchers are sequencing the DNA of young grown-ups and children who suffer from extreme Covid-19 disease ailments in spite of having no hidden clinical issues. The scientists are …

Study looks at genetic background of healthy people who develop severe Covid-19 illness Read more »

May 07, 2020 – Abdominal aortic aneurysm (AAA) is a localized enlargement of the abdominal aorta such that the diameter is greater than 3 cm or more than 50% larger than normal. AAAs usually cause no symptoms, except during rupture. Occasionally, abdominal, back, or leg …

Abdominal aortic aneurysm: Genetic scoring can identify more men at risk Read more »

March 05, 2020 – Idiopathic pulmonary fibrosis (IPF) is a type of chronic scarring lung disease characterized by a progressive and irreversible decline in lung function. Symptoms typically include gradual onset of shortness of breath and a dry cough. Other …

Three idiopathic pulmonary fibrosis (IPF)-associated genes newly identified Read more »

February 20, 2020 – Traditional cardiovascular risk factors often assessed in an annual physical, such as blood pressure, cholesterol levels, diabetes, and smoking status, may at least be as valuable in predicting who will develop coronary heart disease (CHD) as …

Heart disease prediction by traditional risk factors as good as with an exhaustive genetic test Read more »

February 01, 2020 – Soccer headers might be more risky for APOE4 genotype carriers – this is the headline of a very recent Reuters Health article appearing in Medscape. Thus, soccer players with apolipoprotein E4 (APOE4) genotype may want to …

Soccer Headers Might Be More Risky for APOE4 Genotype Carriers Read more »

January 26, 2020 – An effort to map thousends of genomes across Asia has certainly the potential to find novel gene variants affecting disease and responses to drugs, and to reveal the complex origins of Asian populations. In a pilot …

The diversity of Asian genomes Read more »