March 20, 2025 – Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide, with approximately 20% of patients presenting with metastatic disease at the time of diagnosis. Despite the cancer’s long progression time, often 5–10 years, …

Does AI unlock genetic keys to improve colorectal cancer survival? Read more »

March 10, 2025 – Does a gene variant shield against the COPA syndrome, a devastating inherited disease? The COPA syndrome is a recently described autosomal dominant inborn error of immunity characterized by high titer autoantibodies and interstitial lung disease, with many …

Does the gene variant HAQ-STING shield against the COPA syndrome? Read more »

March 30, 2025 – A new study from Queen Mary University of London found that 9% of all reported adverse drug reactions (ADRs) reported to the UK medicines regulator are associated with medications where side effect risk is partly dependent …

Can testing for three genes prevent 75% of avoidable side effects for certain medications? Read more »

February 20, 2025 – Black patients with metastatic breast cancer (mBC) showed distinct genomic profiles, including higher rates of specific genetic variants, compared with White patients. Despite equal incidence of PIK3CA alterations, women of color (“black patients”) were significantly less …

Treatment disparity in mBC between women of color and white women Read more »

December 30, 2024 – Transthyretin cardiac amyloidosis (TTR-CA) is now increasingly becoming recognized as an important cause of heart failure, and some studies have shown that as much as a third of diastolic heart failure could be attributed to TTR-CA. …

Uneven burden of cardiac amyloidosis in people of African descent Read more »

December 26, 2024 – Breast cancer is the second most common cancer in women, with 297,790 estimated new cases in the United States in 2023. The relatively high 5-year overall survival of 90.8% indicates that the disease is curable. The …

Decode cause of aggressive breast cancer in Women of Color Read more »

December 09, 2024 – Covid-19 (SARS-CoV-2): Many children worldwide are suffering from the consequences of an acute Covid-19 infection in the form of the do-called Long Covid. This article/post is the form of a corresponding article edited by thasso which originally …

Long Covid: Children diagnosed with ME/CFS Read more »

November 25, 2023 – Sickle cell anemia  is an inherited disease of red blood cells (erythrocytes). It belongs to the group of hemoglobinopathies (hemoglobin disorders) and leads to corpuscular hemolytic anemia. Affected people have a mutation in the hemoglobin β …

Sickle cell anemia: Genetic scissors drug approved for first time Read more »

August 04, 2023 – We at thasso recently had an article (blog) on the much discussed and recently throughout the social media as wonder compound (drug) for weight loss promoted active ingredient Semaglutide in the form of the newly marketed product …

Is there living pharmacogenovigilance behind Semaglutide drugs? Read more »

01 May, 2023 – SARS-CoV-2, like other respiratory viruses, typically initiates infection in the throat and sinuses. But it often spreads from the respiratory tract to other parts of the body, such as the gut, liver, heart, kidneys, brain, blood …

Study identifies human genes enabling SARS-CoV-2 infection Read more »