Genetic Susceptibility

Blog Archives

Heart disease prediction by traditional risk factors as good as with an exhaustive genetic test

Posted on February 20, 2020 by by

Joseph Gut - thasso Posted in Genetic Background, Genetic Predisposition, Genetic Susceptibility, Personalized Medicine, Personomics, Thasso Post, Theragenomic Medicine No Comments ↓

February 20, 2020 – Traditional cardiovascular risk factors often assessed in an annual physical, such as blood pressure, cholesterol levels, diabetes, and smoking status, may at least be as valuable in predicting who will develop coronary heart disease (CHD) as a sophisticated genetic test that surveys millions of different points in DNA,

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Soccer Headers Might Be More Risky for APOE4 Genotype Carriers

Posted on February 1, 2020 by by

Joseph Gut - thasso Posted in Allelic Variant, Genetic Background, Genetic Predisposition, Genetic Susceptibility, In The Press, New Research, Thasso Post, Theragenomic Medicine No Comments ↓

February 01, 2020 – Soccer headers might be more risky for APOE4 genotype carriers – this is the headline of a very recent Reuters Health article appearing in Medscape. Thus, soccer players with apolipoprotein E4 (APOE4) genotype may want to limit how many headers they do,

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The diversity of Asian genomes

Posted on January 26, 2020 by by

Joseph Gut - thasso Posted in Allelic Variant, Ethnicity, Genetic Background, Genetic Predisposition, Genetic Susceptibility, New Research, Thasso Post, Theragenomic Medicine, Theragenomics 1 Comment ↓

January 26, 2020 – An effort to map thousends of genomes across Asia has certainly the potential to find novel gene variants affecting disease and responses to drugs, and to reveal the complex origins of Asian populations.

In a pilot study,

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Tags: Allelic Variant, Asian Origin, Asian Population, Ethnicity, Gene Variant, Genetic Diversity, Thasso Post, Theragenomic Medicine

Degree of African ancestry may influence gene expression levels

Posted on January 26, 2020 by by

Joseph Gut - thasso Posted in Allelic Variant, Ethnicity, Gene Expression, Genetic Susceptibility, New Research, Thasso Post, Theragenomic Medicine No Comments ↓

January 26, 2020 – Common belief holds that differences in genes (i.e., allelic variants) in combination with differing frequencies of such allelic variants in populations of different ethnic background may explain the differences in the frequency and/or severity of overt diseases in different ethnic groups and/or populations.

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In Caribbeans cystic fibrosis (CF) is driven by very rare CFTR mutations

Posted on November 3, 2019 by by

Joseph Gut - thasso Posted in Allelic Variant, Ethnicity, Genetic Predisposition, Genetic Susceptibility, Personalized Medicine, Thasso Post, Theragenomic Medicine No Comments ↓

November 03, 2019 – Cystic fibrosis (CF) is a lethal, inherited genetic disease affecting more than 70,000 people worldwide. It is usually diagnosed in childhood and causes abnormal buildup of thick mucus in the lungs and digestive tract that leads to trouble breathing,

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After an over the counter genetic test: Would you make serious health decisions?

Posted on October 27, 2019 by by

Joseph Gut - thasso Posted in Allelic Variant, Genetic Background, Genetic Predisposition, Genetic Susceptibility, Thasso Post, Theragenomic Medicine No Comments ↓

October 27, 2019 – Genetic tests sold online and in shops are en vogue. More and more patients strive for it, and they (the patients) are getting back results. Results, the normal patient has no chance to understand. Not even most of treating physicians are capable to interpret in favour of their patients.

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Hidden secrets in African genomes revealed by large scale sequencing

Posted on October 20, 2019 by by

Joseph Gut - thasso Posted in Ethnicity, Genetic Background, Genetic Predisposition, Genetic Susceptibility, Thasso Post, Theragenomic Medicine No Comments ↓

October 20, 2019 – Sequencing African genomes yields new data resource with broad applicability. By collaborating globally in a new, large-scale effort, researchers have made strong progress in sequencing genomes from regions and countries across Africa. These findings will enable more broadly representative and relevant studies ranging from basic through clinical genetics.

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Clinical evidence and implementation challenges for pharmacogenomic testing

Posted on September 18, 2019 by by

Joseph Gut - thasso Posted in Allelic Variant, Genetic Background, Genetic Predisposition, Genetic Susceptibility, Personalized Medicine, Personomics, Pharmacogenetics, Thasso Post, Theragenomic Medicine No Comments ↓

September 18, 2019 – This post is an edited version of parts of a paper that appeared in the Journal of Personalised Medicine (JPM) a week ago und which addresses one of the important topics in connection with the themes of personalised medicine,

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ZRANB3 in African Populations: New Type 2 Diabetes risk locus identified

Posted on August 3, 2019 by by

Joseph Gut - thasso Posted in Ethnicity, Genetic Background, Genetic Predisposition, Genetic Susceptibility, Personalized Medicine, Personomics, Thasso Post, Theragenomic Medicine No Comments ↓

August 03, 2019 – Africa is considered the original cradle of all humanity, to which all humans can trace their genetic origin. This may be very interesting in the context of diseases that are due to genetic predispositions both in todays African populations and in all the populations descendant of African origin worldwide.

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Genetic aspects of globesity: Glocalized or not?

Posted on June 25, 2019 by by

Joseph Gut - thasso Posted in Allelic Variant, Gene Expression, Genetic Background, Genetic Predisposition, Genetic Susceptibility, New Research, Personomics, Thasso Post, Theragenomic Medicine No Comments ↓

June 25, 2019 – The global obesity epidemic is so far-reaching it now has an overarching name: globesity (obviously derived from global obesity). Very interesting questions arise in this context such as are there glocalized (global and or local) factors involved in this epidemic.

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