the new generation glocalized patient network in theragenomic and personalized medicine and individualized drug safety
December 28, 2020 – Some 95% of people have gene variants that may negatively affect their response to at least one drug, leading to unexpected or adverse drug reactions (ADRs) or, if unlucky, to a serious, if not fatal, adverse …
Genetics behind some serious adverse drug reactions (SADRs) Read more »
November 19, 2020 – Does genetic variation gives rise to differences in mathematical ability? Based on the observation that certain individuals can solve a simple mental arithmetic, such as the square root of nine, in a split second while other …
Two times two equals five. Some of the genetics behind mathematical capability Read more »
June 13, 2020 – To help disentangle the secrets of Covid-19 disease, researchers are sequencing the DNA of young grown-ups and children who suffer from extreme Covid-19 disease ailments in spite of having no hidden clinical issues. The scientists are …
Study looks at genetic background of healthy people who develop severe Covid-19 illness Read more »
April 28, 2020 – Coronavirus disease 2019 (Covid-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was first identified in December 2019 in Wuhan, the capital of China’s Hubei province, and has since spread globally, …
Could DNA testing help the most seriously affected Covid-19 patients? Read more »
April 24, 2020 – The klotho gene is named after the fanciful Greek goddess of destiny Clotho who turns the string of life known to be related with longer life and improved cognizance. In modern biology, allelic variants of the …
Klotho’s role in some patients with Alzheimer’s disease revealed? Read more »
April 12, 2020 – The human genetic disease neurofibromatosis type 1 (NF-1) is a complex multi-system disorder caused by the mutation of a gene (NF1 gene) on chromosome 17 that is responsible for production of a protein called neurofibromin which is …
First therapy for children with debilitating NF-1 approved in the USA Read more »
March 15, 2020 – An international study published in the journal Cell has described 109 genetic variants associated with eight psychiatric disorders such as autism, ADHD, schizophrenia, bipolar disorder, depression, obsessive-compulsive disorder and Tourette syndrome in a total of about 230,000 …
Large genetic map of psychiatric disorders completed Read more »
March 05, 2020 – Idiopathic pulmonary fibrosis (IPF) is a type of chronic scarring lung disease characterized by a progressive and irreversible decline in lung function. Symptoms typically include gradual onset of shortness of breath and a dry cough. Other …
Three idiopathic pulmonary fibrosis (IPF)-associated genes newly identified Read more »
February 28, 2020 – A very recent report elucidates the possible prospective power of the knowledge about the genetic background of patients when concerned with certain clinical endpoints (disease states) and associated genes. The researchers in the present study analyzed outcomes …
HSD3B1 Genotype Predicts Prostate Cancer Outcomes Read more »
February 27, 2020 – Thiopurines are important antimetabolite drugs, which make up a critical part of curative treatment for ALL. Genetic variations can directly influence drug toxicity and effectiveness of thiopurines. Researchers at St. Jude and elsewhere previously identified NUDT15 …
Genetic variants of the NUDT15 gene drive toxicity in leukemia therapy Read more »