April 28, 2020 – Coronavirus disease 2019 (Covid-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was first identified in December 2019 in Wuhan, the capital of China’s Hubei province, and has since spread globally, …

Could DNA testing help the most seriously affected Covid-19 patients? Read more »

Tagged with: , , , , , , , , , , , , , ,

April 12, 2020 – The human genetic disease neurofibromatosis type 1 (NF-1) is a complex multi-system disorder caused by the mutation of a gene  (NF1 gene) on chromosome 17 that is responsible for production of a protein called neurofibromin which is …

First therapy for children with debilitating NF-1 approved in the USA Read more »

Tagged with: , , , , , , , , , , , , , , ,

February 28, 2020 – A very recent report elucidates the possible prospective power of the knowledge about the genetic background of patients when concerned with certain clinical endpoints (disease states) and associated genes. The researchers in the present study analyzed outcomes …

HSD3B1 Genotype Predicts Prostate Cancer Outcomes Read more »

Tagged with: , , , , , , , , , ,

February 27, 2020 – Thiopurines are important antimetabolite drugs, which make up a critical part of curative treatment for ALL. Genetic variations can directly influence drug toxicity and effectiveness of thiopurines. Researchers at St. Jude and elsewhere previously identified NUDT15 …

Genetic variants of the NUDT15 gene drive toxicity in leukemia therapy Read more »

Tagged with: , , , , , , , ,

February  06, 2020 – Some of the first biological evidence of the incongruence transgender individuals experience, because their brain indicates they are one sex and their body another, may have been found in estrogen receptor pathways in the brain of …

Brain, Body Incongruence in Transgenders: Gene Variants Provide Some Insights Read more »

Tagged with: , , , , , , , , , , , , , , , , , , , , , , , , , , ,

February 01, 2020 – Soccer headers might be more risky for APOE4 genotype carriers – this is the headline of a very recent Reuters Health article appearing in Medscape. Thus, soccer players with apolipoprotein E4 (APOE4) genotype may want to …

Soccer Headers Might Be More Risky for APOE4 Genotype Carriers Read more »

Tagged with: , , , , , , , , ,

January 26, 2020 – An effort to map thousends of genomes across Asia has certainly the potential to find novel gene variants affecting disease and responses to drugs, and to reveal the complex origins of Asian populations. In a pilot …

The diversity of Asian genomes Read more »

Tagged with: , , , , , , ,

January 26, 2020 – Common belief holds that differences in genes (i.e., allelic variants) in combination with differing frequencies of such allelic variants in populations of different ethnic background may explain the differences in the frequency and/or severity of overt …

Degree of African ancestry may influence gene expression levels Read more »

Tagged with: , , , , , , , , ,

August 07, 2019 – Blonde hair is a rare human phenotype found almost exclusively in Europe and Oceania. Human pigmentation varies considerably within and among populations and is a function of both variation in exposure to ultraviolet radiation (UVR) and …

Black people with natural blonde hair – Everything is possible in genetics Read more »

Tagged with: , , , , , , , , , , , , , , , ,

June 25, 2019 – The global obesity epidemic is so far-reaching it now has an overarching name: globesity (obviously derived from global obesity).  Very interesting questions arise in this context such as are there glocalized (global and or local) factors …

Genetic aspects of globesity: Glocalized or not? Read more »

Tagged with: , , , , , , , , , ,