Blog Archives

Is laziness a personal choice or a genetic trait?

November 02, 2019 – Is laziness a choice or genetic trait? At the age where genetics seems to explain everything, it is certainly interessant to learn that a seemingly personal choice such as laziness as such may loom somewhere in your genetic outfit. Perhaps, you can not escape your laziness behaviour,

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Hidden secrets in African genomes revealed by large scale sequencing

October 20, 2019 – Sequencing African genomes yields new data resource with broad applicability. By collaborating globally in a new, large-scale effort, researchers have made strong progress in sequencing genomes from regions and countries across Africa. These findings will enable more broadly representative and relevant studies ranging from basic through clinical genetics.

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Black people with natural blonde hair – Everything is possible in genetics

August 07, 2019 – Blonde hair is a rare human phenotype found almost exclusively in Europe and Oceania. Human pigmentation varies considerably within and among populations and is a function of both variation in exposure to ultraviolet radiation (UVR) and the type and quantity of melanin produced in melanocytes and keratinocytes.

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Chinese arrhythmia in traditional medicine

May 04, 2018 – All natural is healthy. This is a common belief for many, particularly when shopping for alternative medicines and dietary supplements. For many, however, the contrary might be fatally true.

As a point in case, new research shows, that substances in Traditional Chinese Medicine  (TCM) can cause severe cardiac arrhythmia. 

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Placebo: A veritable treatment option

February 11, 2018 – Long after cancer treatment ends, many patients continue to deal with one particular symptom that refuses to go away: fatigue. In a new study, researchers have found that the power of placebos, even when fully disclosed to patients, might be harnessed to reduce fatigue in cancer survivors.

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Chocolate and the sweet taste receptor gene TAS1R2

January 31, 2018 – Chocolate and the sweet taste receptor gene TAS1R2 may make the life of some obese children and adolescents rather difficult in that genetic variations in TAS1R2 appear related to chocolate powder and dietary fiber intake in these young individuals.

This comes out of a study by a research team at the Faculty of Medicine,

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Ashkenazi Jewish Women: Little-known Gene Mutations May Boost Breast Cancer Risk

July 27, 2017 – Jewish women of Ashkenazi descent may be at risk for additional genetic mutations that increase their risk of breast cancer, according to a new study just published in JAMA Oncology. Researchers from University of Washington in Seattle found that around 4 percent of Ashkenazi Jewish women without well-known founder mutations in BRCA1 and BRCA2 genes have other mutations that may increase their risk for breast cancer.

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Genetic Biomarker Tied to Suicide Risk in Schizophrenia

 July 18, 2017 – According to a new study just published in the Journal of  Psychiatric Research, a single-nucleotide polymorphism (SNP), rs300774, which previously had been identified as a marker for suicide in people with bipolar disorder (BD), also predicts suicide attempts in people with schizophrenia (SCZ) or schizoaffective disorder (SAD).

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Genetic Study Strengthens Causal Role of BMI in Heart Disease

July 07, 2017 – A new study analyzing genetic mutations predisposing to increased body-mass index (BMI) provides strong evidence that higher BMI plays a causal role in type 2 diabetes, hypertension, and coronary heart disease (CHD). The study results strongly suggest that BMI is causally related to increased risk of developing diabetes,

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Genetic background of insomnia: At least partially

June 20, 2017 – Insomnia is one of the most common complaint people have about their health. In contrast to common belief and often assumed by the affected sufferers, however, insomnia seems not to be just all in the patients head. A large genome wide association study (GWAS),

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  • Protein AKAP8 suppresses breast cancer metastasis January 27, 2020
    A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. Researchers led by Baylor College of Medicine also found that high levels of this protein, AKAP8, predicts a better survival for breast cancer patients.
  • The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis January 27, 2020
    The cover for issue 3 of Oncotarget features Figure 3, "Hierarchical clustering of tonsil squamous cell carcinoma cohorts based on viral signature detection pattern with associated pathological features (perineural invasion (PNI), lymphovascular invasion (LVI), and tumor stage (T stage))," by Carey, et al.
  • Asfotase alfa in hypophosphatasia in childhood/adolescence: Survival benefit for infants January 27, 2020
    Hypophosphatasia (HPP) is a rare congenital metabolic disorder. The frequency of severe courses of disease is estimated at 1:100 000: A deficiency of the enzyme phosphatase results in insufficient mineralization of the bones and thus in severe skeletal malformations. The course of disease varies greatly—the earlier the onset of the disease, the more severe are […]
  • Unrecognized genetic variation in research mouse models can affect immune cells January 27, 2020
    Congenic mouse strains—used for decades in immunology research and assumed to be genetically identical outside of a marker locus—have been found to contain previously unrecognized genetic variation, University of Alabama at Birmingham researchers reported in a study published in the journal Immunity.
  • Genomics experts dispute nine genes linked to congenital heart condition January 27, 2020
    Geneticists and heart specialists around the world had previously reported 17 genes to cause long QT syndrome, a little-known inherited heart condition. However, the Clinical Genome Resource's (ClinGen) expert panel has critically reevaluated the scientific evidence for all 17 reported genes, disputing nine of the genes and revealing only three of the genes to be […]
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