March 27, 2024 – Lyrica (Pregabalin) is a drug from the group of gabapentinoids and is an anticonvulsant active ingredient. It has been approved throughout the EU since 2004 for the treatment of neuropathic pain, epilepsy and generalized anxiety disorder. …

Lyrica (Pregabalin): Thousands of deaths? Read more »

December 11, 2023 – In June of 2021, the American Food and Drug Administration (FDA) approved the drug semaglutide for chronic weight management under the brand name Wegovy, ushering in a new era of obesity treatment. Since then, demand for …

Semaglutide Popularity: Serious Rare Adverse Effects Are Emerging Read more »

August 04, 2023 – We at thasso recently had an article (blog) on the much discussed and recently throughout the social media as wonder compound (drug) for weight loss promoted active ingredient Semaglutide in the form of the newly marketed product …

Is there living pharmacogenovigilance behind Semaglutide drugs? Read more »

July 20, 2023 – The SARS-CoV-2 virus has changed the lives of millions and millions of individuals worldwide. It has also changed the behaviour of the society as a whole with respect to more aggressive and less tolerant behaviour of …

Separating falsehoods from facts: Long Covid and Vaccines Read more »

March 18, 2023 – Valtrex (Valacyclovir) is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. It is a prodrug, …

Canada: DRESS Syndrome associated with Valtrex (Valacyclovir) Read more »

December 22, 2022 – Are the many effects of ketamine clinically manageable? For treating clinicians and their patients receiving ketamine for quite a number of indications such as starting and maintaining general anesthesia, some forms of chronic pain relief, and some types …

Ketamine, Depression, Addiction: Is it a Cure, a Cause or a Vicious Cycle? Read more »

November 20, 2022 – The genetics of drug side-effects. Some 95% of people have a gene variant that affects their response to at least one drug. Treating physicians, clinical researchers, and affected patients know all to well the serious problems that …

Is there pre-emptive genotyping to avoid adverse drug effects (ADRs)? Read more »

October 14, 2022 – “Gambia Police Link Child Deaths to Cough Syrups Imported by US Firm”. This is a report from Reuters that illustrates in a tragic fashion the problem of globalisation of all processes involved in providing medicines to the needing …

The Gambia: Childrens deaths due to cough syrups Read more »

August 26, 2022 – Traditionally, pharmacovigilance (PV), is the pharmaceutical science relating to the “collection, detection, assessment, monitoring, and prevention” of adverse drug reactions (ADRs) with pharmaceutical products and associated therapies. Pharmacovigilance is based on information about ADRs received from patients and healthcare …

Pharmacogenovigilance: Has the time come? Read more »

August 21, 2022 – Systemic lupus erythematosus (SLE) is a common, incurable autoimmune disease that affects millions of individuals worldwide, with a particularly high prevalence among women. A genetic variant, called HLA-DRB1*03:01, is the greatest risk factor for the condition, …

Serious lupus: Strong genetic risk factor on its path Read more »