the glocalized network in theragenomic and personalized medicine and the genetics of individual patients safety of drugs
February 20, 2025 – Black patients with metastatic breast cancer (mBC) showed distinct genomic profiles, including higher rates of specific genetic variants, compared with White patients. Despite equal incidence of PIK3CA alterations, women of color (“black patients”) were significantly less …
Treatment disparity in mBC between women of color and white women Read more »
December 30, 2024 – Transthyretin cardiac amyloidosis (TTR-CA) is now increasingly becoming recognized as an important cause of heart failure, and some studies have shown that as much as a third of diastolic heart failure could be attributed to TTR-CA. …
Uneven burden of cardiac amyloidosis in people of African descent Read more »
January 26, 2020 – An effort to map thousends of genomes across Asia has certainly the potential to find novel gene variants affecting disease and responses to drugs, and to reveal the complex origins of Asian populations. In a pilot …
October 20, 2019 – Sequencing African genomes yields new data resource with broad applicability. By collaborating globally in a new, large-scale effort, researchers have made strong progress in sequencing genomes from regions and countries across Africa. These findings will enable …
Hidden secrets in African genomes revealed by large scale sequencing Read more »
August 01, 2019 – Post-Traumatic Stress Disorder (PTSD) is a mental disorder that can develop after a person is exposed to a traumatic event, such as sexual assault, warfare, traffic collisions, or other threats on a person’s life. Symptoms may include disturbing …
Risk loci for post-traumatic stress disorder (PTSD) Read more »
December 09, 2017 – Newest research has revealed that a DNMT3B gene variant influences nicotine dependence identified in people of European (Caucasian) descent and African-American decent as well. Thus, a DNA variant, located in the DNMT3B gene and commonly found …
DNMT3B gene variant influences nicotine dependence Read more »
December 05, 2017 – We are entering the age of precision medicine, in which diagnosis and therapy decisions for each patient will be based on detailed genetic and molecular fingerprints. Unfortunately, much of the revolutionary work that underpins precision medicine has …
November 24, 2017 – New research indicates that one-size treatment for one form of blood cancer likely does not fit all, particularly when it comes to ethnic differences of patients. Thus, African-American men are three times more likely to be …
Cancer is not like cancer: Ethnic background matters Read more »
July 27, 2017 – Jewish women of Ashkenazi descent may be at risk for additional genetic mutations that increase their risk of breast cancer, according to a new study just published in JAMA Oncology. Researchers from University of Washington in Seattle …
Ashkenazi Jewish Women: Little-known Gene Mutations May Boost Breast Cancer Risk Read more »