January 08, 2023 – In precision and/or targeted medicine of today, physicians typically start out with the determination of the patients phenotypic expression of a disease (i.e., establish a clinical finding) and then go on into finding out the patients genetic …

Genomic variants traced forward to genetic disorders: A new approach? Read more »

December 11, 2022 – We’re all familiar with the five senses that allow us to experience our surroundings, namely sight, hearing, smell, taste, and touch. However, equally important but much less well known is the so called Sixth Sense. Sixth sense …

The sixth sense: Are there genes associated with it? Read more »

29. October 2022 – A first clinical guideline on Schaaf-Yang syndrome for professionals and families has been created. Improving knowledge of Schaaf-Yang syndrome (SYS), an ultra-rare disease caused by mutations in the MAGEL2 gene, is the aim of this first clinical …

The extremely rare Schaaf-Yang Syndrome and the MAGEL2 gene Read more »

September 21, 2022 – Here, a big bias in genetic research into its applicability on “personalized”, or “precision”, or “theragenomic” medicine is finally addressed and brought forward to all involved in these fields. The problem until now is (and was} that …

Ethnic equity in precision medicine Read more »

September 03, 2022 – Sometimes, in sleepless nights, as an ever and never stopping inquiring mind, you may stumble over just flabbergastingly mind-boggling stuff like this. The issue is “doppelgänger” and the possible genetic similarities behind it. Doppelgänger means people that …

My doppelgänger: Has he/she my DNA and my genes too? Read more »

21 July 2022 – Blockchain is a digital technology that allows a secure and decentralized record of transactions that is increasingly used for everything from cryptocurrencies to artwork. But blockchain also is entering or is increasingly used in any environment, …

Blockchain: Genomics instead of bitcoins Read more »

13 June 2022 – Sometimes, patients genetics can be bewildering and/or unjust. Common belief with patients and the general public would be that genetic variants would be responsible for causing all kinds of adverse drug reactions (ADR’s) and be at the …

Rare APOE genetic variants reduce Alzheimer’s risk Read more »

April 30, 2022 – In a very recent report published in PLoS Genetics  by Dr. Verma of the Corporal Michael Crescenz VA Medical Center in Philadelphia, Pennsylvania, US, and colleagues, new data from the Veterans Affairs Million Veteran Program (MVP) has …

Genetic links revealed between severe COVID-19 and other diseases Read more »

April 10, 2022 – Sotrovimab, sold under the brand name Xevudy, is a monoclonal antibody that was available under emergency use authorization (EUA) from the FDA and similar urgency authorisations from several drug regulatory agencies worldwide for the treatment of patients …

SARS-CoV-2 Delta Variant: Resistance Mutations after Sotrovimab Use Read more »

March 10, 2022 – In a new report distributed in “Circulation: Genomic and Precision”, scientists showed that as while numerous African Americans, particularly those with a high African Family extent, have a good lipid profile, they are at a higher …

Genetic variations and social health determinants may lead to higher risk for diabetes in individuals with high African heritage Read more »