Blog Archives

Is there a risk of melanoma with erectile dysfunction drugs?

November 01, 2017 – According to the watch list of the American Food & Drug Administration (FDA) for drugs with possible safety issues from January to March 2016,

the FDA was looking at the possible link between various drugs in the phosphodiesterase-5 (PDE-5) inhibitors class and melanoma as a serious adverse effect.

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Happy but blind: A role for erectile dysfunction (ED) drugs

August 26, 2017 – The erectile dysfunction (ED) drugs Tadalafil (Cialis), Vardenafil (Levitra), and even more so Sildenafil (Viagra) have previously been associated with a type of sudden vision loss called Nonarteritic Anterior Ischemic Optic Neuropathy (NAION). According to a recent medical study,

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Granpidam: A generic to Sildenafil (Revatio)

September 22, 2016 – The pharmacologically active compound known as sildenafil is largely used to treat erectile dysfunction (on the market for this indication under the trade name Viagra) and pulmonary arterial hypertension (on the market for this indication under the trade name Revatio) in the United

States (US),

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Stiff Nights: Dangerously tainted sexual enhancement products are everywhere

November 25, 2015 – Right in time for the upcoming holyday season, this post addresses once more the issue of tainted sexual enhancement products. Such products, bought over the counter (OTC) or from Internet stores may pose serious health risks to individuals and turn some  holyday season leisure time activities into a nigthmare for some.

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The “female” Viagra: Will it one day be a commercial success? Approval recommended for Flibanserin (ADDYI) to treat hypoactive sexual desire disorder (HSDD) in premenopausal women

June 5, 2015 – This is an edited post based on a PRNewswire release (see here) which refers to the 2015 June 4th joint meeting of  the U.S. Food and Drug Administration’s (FDA) joint meeting of the Bone, Reproductive and Urologic Drugs Advisory Committee,

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Sildenafil [Revatio]: FDA Clarifies Warning About Pediatric Use for Pulmonary Arterial Hypertension (PAH)

March 31, 2014 –  The American Food and Drug Administration (FDA) is clarifying its previous recommendation related to prescribing Sidenafil [Revatio] for children with pulmonary arterial hypertension (PAH). Note that the pharmacologically active compound sildenafil is also the pharmacologically active principle in Sildenafil [Viagra] which is on the market to treat erectile disfunction.

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  • Mayo researchers recommend all women with breast cancer diagnosis under age 66 be offered genetic testing February 21, 2020
    A study by researchers at Mayo Clinic published this week in the Journal of Clinical Oncology suggests that all women with a breast cancer diagnosis under the age of 66 be offered germline genetic testing to determine if they have a gene mutation known to increase the risk of developing other cancers and cancers among […]
  • Cross-talk between enzymes that read and correct recipes in the cookbook of life February 21, 2020
    DNA is the hereditary material in humans, a unique cookbook of who we are. This is where you'll find the answer as to why you have your specific eye and hair colour, or perhaps why you sunburn easily.
  • Study finds certain genetic tests not useful in predicting heart disease risk February 21, 2020
    A Polygenic Risk Score—a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients—has been found not to be a useful predictive biomarker for disease risk, according to a Vanderbilt study published in the Journal of the American Medical Association.
  • Major discovery in the genetics of Down syndrome February 21, 2020
    Researchers at CHU Sainte-Justine and Université de Montréal have discovered a new mechanism involved in the expression of Down syndrome, one of the main causes of intellectual disability and congenital heart defects in children. The study's findings were published today in Current Biology.
  • MicroRNA exhibit unexpected function in driving cancer February 20, 2020
    Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does, and how the two may be involved in cancer. New research from Thomas Jefferson University has revealed that both strands of some microRNA coordinate to act on […]
  • Ethnobotanical medicine is effective against the bacterium causing Lyme disease February 21, 2020
    A preclinical in vitro study shows that selected plant-based herbal medicines, especially Ghanaian quinine and Japanese knotweed, work better than antibiotics against the bacterium that causes Lyme disease. These findings represent an important step towards the development of treatments that might be better tolerated and more effective than the current standard of care.
  • Opportunity blows for offshore wind in China February 21, 2020
    If China is to meet and exceed its Paris Climate Agreement goal by 2030, it's going to need to find a way to increase its wind capacity. Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) and Huazhong University of Science and Technology in China, found that offshore wind could […]
  • Alcohol-induced deaths in US February 21, 2020
    National vital statistics data from 2000 to 2016 were used to examine how rates of alcohol-induced deaths (defined as those deaths due to alcohol consumption that could be avoided if alcohol weren't involved) have changed in the US and to compare the results by demographic groups including sex, race/ethnicity, age, socioeconomic status and geographic location. […]
  • The integrated catalysts can simplify pharmaceutical manufacturing February 21, 2020
    Prof. In Su Lee and his research team from POSTECH developed catalytic platforms based on metal organic frameworks.
  • Shaping the rings of molecules February 21, 2020
    Canadian chemists discover a natural process to control the shape of 'macrocycles,' molecules of large rings of atoms, for use in pharmaceuticals and electronics.
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