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Thasso the glocalized network in theragenomic and personalized medicine and the genetics of individual patients safety of drugs

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FDA press releases

FDA Approves First Treatment for Children With Menkes Disease January 12, 2026
FDA Issues Guidance on Modernizing Statistical Methods for Clinical Trials January 12, 2026
FDA Increases Flexibility on Requirements for Cell and Gene Therapies to Advance Innovation January 11, 2026
FDA Finds Insufficient Data to Determine Safety of PFAS in Cosmetic Products December 29, 2025
FDA Grants Two National Priority Vouchers December 19, 2025

FDA MedWatch

Organ Recovery Pack Correction: AVID Medical Issues Correction for Medical Convenience and Organ Recovery Kits January 9, 2026
Anthony Trinh, 123Herbals LLC (123HERBALS.COM) Issues Nationwide Recall of Silintan Capsules Due to the Presence of Undeclared Meloxicam January 9, 2026
Modern Warrior Recalls “Modern Warrior Ready” Dietary Supplement Due to Undeclared 1,4-DMAA and Aniracetam, as Well as Tianeptine, Which has Not Been Approved for Supplement Use by the FDA. January 9, 2026
Intravascular PICC Catheter Recall: Bard Removes PowerPICC Intravascular Catheters January 5, 2026
Infusion Pump Software Recall: Baxter Removes Sigma Spectrum Infusion System Platforms January 5, 2026

EMA Press releases

Emer Cooke, EMA’s Executive Director: 2025 achievements in medicine regulation December 19, 2025
EMA Management Board: highlights of December 2025 meeting December 19, 2025
EMA business hours over holiday period December 19, 2025

random genetics

Two wrongs make a right: How two damaging disease variants can restore health January 12, 2026
Scientists at Pacific Northwest Research Institute (PNRI) have overturned a long-held belief in genetics: that inheriting two harmful variants of the same gene always worsens disease. Instead, the team found that in many cases, two harmful variants can actually restore normal protein function.
Whole-genome sequencing may optimize PARP inhibitor use for cancer patients January 12, 2026
A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators. The findings suggest further development of this approach is merited.
Genes that predispose an individual to pancreatic cancer identified January 12, 2026
A new study by the National Cancer Research Center (CNIO) has identified several sets of genes related to the predisposition to develop pancreatic ductal adenocarcinoma (the most common type of pancreatic cancer), as well as the prognosis of the disease once it has appeared.
New mutations in TP53 gene drive resistance to p53-targeted cancer therapy January 12, 2026
Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it creates a small crevice in the mutant protein that is not present in the wild type conformation.
DNA testing of colorectal polyps improves insight into hereditary risks January 12, 2026
For 10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients. Research from Radboud University Medical Center and University Hospital Bonn (UKB) in collaboration with researchers from Munich and Barcelona, shows that DNA analysis of colorectal polyps provides important additional information on the development of these polyps and colorectal […]

Recent Comments

Joseph Gut - thasso on Alzheimer’s: Are we at the beginning of a new era of treatment?: “Finally, Leqembi has now also been approved by the EMA. See https://www.ema.europa.eu/en/medicines/human/EPAR/leqembi#product-info” Jun 23, 08:12
20urbain05 on Orofacial clefts: Can genetic variants reveal how they arise?: “It would be of particular interest, which of the many existing sequence variants of the DDX1 gene is (are) particularly…” Apr 19, 13:33
20justin03 on Molecular differences in pancreatic cancer of patients with Caucasian or African Ethnicity: “Some new knowledge on the aggressivity of pancreatic cancer. Not yet known if this mechanism is more active in some…” Apr 17, 15:43
Joseph Gut - thasso on Semagludite: The cause for NAION and Blood Clots?: “NAION is slowly developing into a case for legal actions, according to Tom Lamb at Drug Injury Watch. https://www.drug-injury.com” Apr 10, 13:48
Joseph Gut - thasso on Molecular differences in pancreatic cancer of patients with Caucasian or African Ethnicity: “Newest research: New hope for patients with pancreatic cancer? https://medicalxpress.com/news/2025-04-proof-concept-approach-pancreatic-cancer.html” Apr 9, 14:02

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Adverse Drug Reaction (ADR) African American Allelic Variant Allelic Variants American Food & Drug Administration (FDA) American Food & Drug Administration (FDA) Biomarker Boxed Warning Breast Cancer Canagliflozin (Invokana) Cancer Children Committee for Medicinal Products for Human Use (CHMP) Companion Test Covid-19 Covid-19 Disease Diabetes Drug Induced Liver Injury (DILI) Ethnicity European Medicines Agency (EMA) Food and Drug Administration (FDA) Gene Therapy Genetic Background Genetic Predisposition Genetic Testing Health Canada Non-Small Cell Lung Cancer (NSCLC) Obesity Pembrolizumab [Keytruda] Personalized Medicine Phenotype Progressive Multifocal Leukoencephalopathy (PML) Rare Disease Rare Genetic Disease Risk Evaluation and Mitigation Strategy (REMS) SARS-CoV-2 Schizophrenia Stevens Johnson Syndrome [SJS] Targeted Therapy ThassoBase Thasso Post Theragenomic Medicine Toxic Epidermal Necrolysis (TEN) Type 2 Diabetes Vemurafenib [Zelboraf]

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