Blog Archives

Tapping into the massive potential of African genomes: 54gene

February 22, 2020 – Genetic studies rely almost entirely on genomes from people of Caucasian descent. While all around the world, tissue and blood banks have sprung up to catalog human genome’s many mysteries, this was not the case for Africa. Until now,

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Soccer Headers Might Be More Risky for APOE4 Genotype Carriers

February 01, 2020 – Soccer headers might be more risky for APOE4 genotype carriers – this is the headline of a very recent Reuters Health article appearing in Medscape. Thus, soccer players with apolipoprotein E4 (APOE4) genotype may want to limit how many headers they do,

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Onasemnogene abeparvovec-xioi (Zolgensma): Approval strategy with manipulated data?

August 13, 2019 – Onasemnogene abeparvovec-xioi (Zolgensma) is an adeno-associated virus vector-based gene therapy indicated for the treatment of pediatric patients less than 2 years of age with spinal muscular atrophy (SMA) with bi-allelic mutations in the survival motor neuron 1 (SMN1) gene.

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Where portrait photos meet genetics and AI

June 13, 2019 – This is simply fascinating stuff. Researchers are testing neural networks that automatically combine portrait photos with genetic and phenotypic patient data in order to obtain definitive diagnosis of hereditary rare diseases, all with the help of artificial intelligence (AI).  

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The Post Finasteride Syndrome (PFS): Are young men left alone until up to suicide?

February 20, 2017 – Finasteride,  is a medication used for the treatment of benign prostatic hyperplasia (on the market as Proscar (5mg) since 1992 for this indication) and male pattern hair loss (on the market as Propecia (1mg) since 1997 for this indication).

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Stuff to read: Why should our Y chromosome disappear, after all?

January 21, 2019 – Stuff to Read: As the Y chromosome is disappearing, we prepare ourselves to say goodbye to men, while asking if we could, and/or should, engineer animals to be as smart as us as humans?

As the person behind thasso.com and the writer of some of the posts to be found on thasso post,

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Is there breast implant-associated cancer (BIA-ALCL)?

January 09, 2019 – Women should be alerted: Is there a thing like breast implant associated cancer (BIA-ALCL)? Yes, there is. Not every woman with a breast implant will get it, however. In fact, BIA-ALCL seems to be a rather rare condition; unfortunately,

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CRISPR/Cas9 for the Treatment of Duchenne Muscular Dystrophy: Prime time already?

December 12, 2018 – The application of CRISPR/Cas9 based molecular technology in the field of gene editing (or genome editing) has recently had its exploded limelight exposure for a couple of reasons. The question arises if this exposure is earned or somewhat premature.

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Risk of Bullous Pemphigoid with Type 2 Diabetes Drugs

August 12, 2018 – Findings from a retrospective case-control study were published online August 8, 2018, in JAMA Dermatology indicate that the use of certain dipeptidyl peptidase 4 (DPP-4) inhibitor drugs are associated with a small but significantly elevated risk for developing bullous pemphigoid,

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Ethnic disparities in the occurrence of prostate cancer

May 10, 2018 – A seemingly higher incidence of prostate cancer and resulting fatalities in African-American men than in European-Amcerican men has been noted for quite some time. New research published in Molecular Oncology may help explain why African American men are at a higher risk of being diagnosed with prostate cancer and a higher risk of dying from the disease compared with European American men.

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  • The genetics of side-effects November 25, 2020
    Henk-Jan Guchelaar knows all too well the serious problems that the side-effects of medication can cause. As a professor of clinical pharmacy at the University of Leiden in the Netherlands, he has spent the last two decades trying to get the link between medicine and our genes recognised more widely.
  • Gene donors at high risk for cancer received feedback November 25, 2020
    Researchers at the Estonian Genome Center at the University of Tartu studied how people at high risk for breast, ovarian or prostate cancer responded to the feedback of genetic findings. Gene donors who chose to receive results appreciated being contacted and considered the information provided to be valuable. Authors find that knowing more about people's […]
  • Researchers reveal how genetic variations are linked to COVID-19 disease severity November 25, 2020
    Even as tens of thousands of Americans test positive for COVID-19 each day, physicians still aren't sure why some people experience mild to no symptoms while others become critically ill. New research led by Robert E. Gerszten, MD, Chief of the Division of Cardiovascular Medicine at Beth Israel Deaconess Medical Center (BIDMC) sheds new light […]
  • Study identifies new functions in the gene that causes Machado-Joseph disease November 25, 2020
    Ataxia is a minority disease with genetic origins, known for its neuromuscular alterations due to the selective loss of neurons in the cerebellum, the organ of our nervous systems which controls movement and balance. UB researchers have identified new functions in the ataxin 3 gene (ATXN3)–which causes Machado-Joseph disease, the most common type of ataxia– […]
  • BICRA gene provides answers to patients, doctors and scientists November 23, 2020
    Physicians and scientists are constantly on the lookout for new disease genes that can help them understand why patients have undiagnosed medical problems. Often the first clues come from genetic testing that reveals a change or mutation in a gene that they see in a child but not their parents. This is exactly what led […]
  • Understanding traditional Chinese medicine can help protect species November 26, 2020
    Demystifying traditional Chinese medicine for conservationists could be the key to better protecting endangered species like pangolins, tigers and rhino, according to University of Queensland-led researchers. UQ PhD candidate Hubert Cheung said efforts to shift entrenched values and beliefs about Chinese medicine are not achieving conservation gains in the short term.
  • Satellite images confirm uneven impact of climate change November 26, 2020
    University of Copenhagen researchers have been following vegetation trends across the planet's driest areas using satellite imagery from recent decades. They have identified a troubling trend: Too little vegetation is sprouting up from rainwater in developing nations, whereas things are headed in the opposite direction in wealthier ones. As a result, the future could see […]
  • Survival protein may prevent collateral damage during cancer therapy November 25, 2020
    Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies. The 'cell survival protein', called BCL-XL, was required in laboratory models to keep kidney cells alive and functioning during exposure to chemotherapy or radiotherapy. Kidney damage is a common side effect of these widely used cancer therapies, […]
  • New discovery by SMART allows early detection of shade avoidance syndrome in plants November 25, 2020
    Researchers from Singapore-MIT Alliance for Research and Technology (SMART) have developed a tool that allows early detection of shade avoidance syndrome (SAS) in plants using Raman spectroscopy in significantly less time compared to conventional methods. The discovery can help farmers better monitor plant health and lead to improved crop yield.
  • Psychological factors contributing to language learning November 25, 2020
    Motivation for language learning is a system of cognitive, emotional, and personality-related characteristics.
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