December 30, 2024 – Transthyretin cardiac amyloidosis (TTR-CA) is now increasingly becoming recognized as an important cause of heart failure, and some studies have shown that as much as a third of diastolic heart failure could be attributed to TTR-CA. …

Uneven burden of cardiac amyloidosis in people of African descent Read more »

December 26, 2024 – Breast cancer is the second most common cancer in women, with 297,790 estimated new cases in the United States in 2023. The relatively high 5-year overall survival of 90.8% indicates that the disease is curable. The …

Decode cause of aggressive breast cancer in Women of Color Read more »

Doctor showing his patient her colonoscopy report..

May 06, 2024 –  Non-Hispanic persons of African ancestry typically have worse clinical outcomes from colorectal cancer (CRC) than individuals of other heritages, a disparity attributed to many factors, including socioeconomic, environmental, and genetic influences, as well as less access …

African Ancestry Linked to Worse CRC Outcomes Read more »

03 January 2024 – 23andMe is a  personal genomics company out of  South San Francisco, It is best known for providing a direct-to-consumer (DTC) genetic testing service in which customers provide a saliva sample that is laboratory analysed, using single nucleotide polymorphism …

23andMe: Expansion in BRCA1/BRCA2 Genetic Tests Read more »

March 01, 2023 – The gene APOE codes for apolipoprotein E (Apo-E), a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in the Alzheimer’s disease and cardiovascular diseases. Recently, researchers at Stanford University …

APOE Missense Variant Linked to Increased Alzheimer’s Disease Risk in African Americans Read more »

November 10, 2022 – Drug addiction is a huge social problem of our todays societies. The problem does not only exist in the USA, but in other countries worldwide as well, with enormous numbers of victims due to alcoholism, smoking, …

Do genes affect our risk for addiction? Read more »

August 21, 2022 – Systemic lupus erythematosus (SLE) is a common, incurable autoimmune disease that affects millions of individuals worldwide, with a particularly high prevalence among women. A genetic variant, called HLA-DRB1*03:01, is the greatest risk factor for the condition, …

Serious lupus: Strong genetic risk factor on its path Read more »

August 18, 2022 – The question why certain patients suffer from very severe, even fatal conditions after infections with SARS-CoV-2 has occupied patients, the general population, medical professionals, and the media all alike for some time now. As a basic researcher …

Do genomic regions influence the severity of Covid-19 disease? Read more »

29 July 2022 – This is a mind-boggling article out of the MedicalXpress news portal, which I present here almost original and unedided. So, all the credentials go to the authors at MedicalXpress. Here the article: The Rady Children’s Institute for …

Is there rapid management of 500 (rare) genetic diseases? Read more »

13 June 2022 – Sometimes, patients genetics can be bewildering and/or unjust. Common belief with patients and the general public would be that genetic variants would be responsible for causing all kinds of adverse drug reactions (ADR’s) and be at the …

Rare APOE genetic variants reduce Alzheimer’s risk Read more »