Joseph Gut - thasso
Posted in Allelic Variant, Genetic Predisposition, Genetic Susceptibility, New Research, Thasso Post, Theragenomic Medicine
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October 15, 2020 – SARS-CoV-2 and its resulting disease, Covid-19 disease, is (still) rattling the world. It still remains largely unknown, at this point in time, which are the infected individuals who fall very seriously, even fatally, ill with Covid-19 disease. Of course,
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Joseph Gut - thasso
Posted in Allelic Variant, Genetic Background, Genetic Predisposition, New Research, Personomics, Thasso Post, Theragenomic Medicine
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April 28, 2020 – Coronavirus disease 2019 (Covid-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was first identified in December 2019 in Wuhan, the capital of China’s Hubei province,
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Joseph Gut - thasso
Posted in Allelic Variant, Genetic Background, Genetic Predisposition, New Research, Personomics, Thasso Post, Theragenomic Medicine
1 Comment ↓
Joseph Gut - thasso
Posted in Adverse Drug Reaction [ADR], Allelic Variant, Ethnicity, Genetic Predisposition, Personalized Medicine, Thasso Post, Theragenomic Medicine
1 Comment ↓
March 10, 2020 – A widespread assumption is, the people of Asian descent are more prone to serious, sometimes deadly adverse drug reactions, even when taking rather common medications prescribed for gout through to depression. In the ages of genetics and precision medicine, the question then comes up if Asian people could be at such heightened risk because of underlying particular genetic factors.…
Joseph Gut - thasso
Posted in Allelic Variant, Genetic Background, Genetic Predisposition, Thasso Post, Theragenomic Medicine
3 Comments ↓
March 15, 2020 – An international study published in the journal Cell has described 109 genetic variants associated with eight psychiatric disorders such as autism, ADHD, schizophrenia, bipolar disorder, depression, obsessive-compulsive disorder and Tourette syndrome in a total of about 230,000 patients worldwide.
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Joseph Gut - thasso
Posted in Allelic Variant, Genetic Background, Genetic Predisposition, New Research, Thasso Post, Theragenomic Medicine
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February 28, 2020 – A very recent report elucidates the possible prospective power of the knowledge about the genetic background of patients when concerned with certain clinical endpoints (disease states) and associated genes.
The researchers in the present study analyzed outcomes in white men enrolled in the E3805 CHAARTED clinical trial according to HSD3B1 genotype,
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Joseph Gut - thasso
Posted in Allelic Variant, Genetic Background, Genetic Predisposition, New Research, Thasso Post, Theragenomic Medicine
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February 27, 2020 – Thiopurines are important antimetabolite drugs, which make up a critical part of curative treatment for ALL. Genetic variations can directly influence drug toxicity and effectiveness of thiopurines. Researchers at St. Jude and elsewhere previously identified NUDT15 variants as a major genetic cause of toxicity during thiopurine therapy,
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Joseph Gut - thasso
Posted in Allelic Variant, Genetic Background, Regulatory Approval, Thasso Post, Theragenomic Medicine
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February 26, 2020 – Fragile X syndrome (FXS) is a genetic disorder characterized by mild-to-moderate intellectual disability.The average IQ in males is under 55, while about two thirds of females are intellectually disabled. Physical features may include a long and narrow face,
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Joseph Gut - thasso
Posted in Allelic Variant, Genetic Background, New Research, Personomics, Thasso Post, Theragenomic Medicine
No Comments ↓
February 06, 2020 – Some of the first biological evidence of the incongruence transgender individuals experience, because their brain indicates they are one sex and their body another, may have been found in estrogen receptor pathways in the brain of 30 transgender individuals.
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Joseph Gut - thasso
Posted in Allelic Variant, Ethnicity, Genetic Background, Genetic Predisposition, Genetic Susceptibility, New Research, Thasso Post, Theragenomic Medicine, Theragenomics
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January 26, 2020 – An effort to map thousends of genomes across Asia has certainly the potential to find novel gene variants affecting disease and responses to drugs, and to reveal the complex origins of Asian populations.
In a pilot study,
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