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Cancer therapies: Immune checkpoint inhibitors may kill you

Posted on October 21, 2018 by by

October 21, 2018 – In a study published online September 13 in JAMA Oncology, the authors just reminded us of the fact that besides all hype about immune checkpoint inhibitors (ICIs) in the cancer therapy field,

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Diabetes: No end to SGLT2-inhibitor drugs side effects

Posted on September 1, 2018 by by

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01 September 2018 – The American Food and Drug Administration (FDA) is warning that cases of a very rare but serious infection of the genitals and area around the genitals have been reported with the class of type 2 diabetes medicines called sodium-glucose cotransporter-2 (SGLT2) inhibitors.

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Patisiran (Onpattro): First targeted RNA-based therapy approved to treat hATTR

Posted on August 13, 2018 by by

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August 14, 2018 – The American Food and Drug Administration (FDA) just approved Patisiran (Onpattro) infusion for the treatment of peripheral nerve disease (polyneuropathy) caused by hereditary transthyretin-mediated amyloidosis (hATTR) in adult patients.

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Risk of Bullous Pemphigoid with Type 2 Diabetes Drugs

Posted on August 12, 2018 by by

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August 12, 2018 – Findings from a retrospective case-control study were published online August 8, 2018, in JAMA Dermatology indicate that the use of certain dipeptidyl peptidase 4 (DPP-4) inhibitor drugs are associated with a small but significantly elevated risk for developing bullous pemphigoid,

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Ivosidenib (Tibsovo) for AML-patients with IDH1-mutations

Posted on July 22, 2018 by by

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July 22, 2018 – The American Food and Drug Administration (FDA) just approved Ivosidenib (Tibsovo) for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation in the IDH1 gene.

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Coffee Drinking, Genetic Variation, and Mortality

Posted on July 7, 2018 by by

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Erenumab-Aooe (Aimovig): Novel preventive treatment for migraine approved

Posted on June 29, 2018 by by

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Epidiolex: Marijuana-derived drug to treat rare forms of epilepsy

Posted on June 26, 2018 by by

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June 26, 2018 – The American Food and Drug Administration (FDA) just approved Cannabidiol (Epidiolex), for the treatment of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome, two rare and severe forms of epilepsy, in patients two years of age and older.

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Winning the FIFA World-Cup: Is it all genetic?

Posted on June 24, 2018 by by

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Midway through the Soccer World Cup 2018 – Granted, the author of this article (that’s me) is addicted to soccer on several levels. For one, I have played football (same as soccer for the world outside the US) as a goal keeper myself; not at the highest performance levels,

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Neural tube defects with Dolutegravir-based HIV medications

Posted on May 21, 2018 by by

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May 22, 2018 –The American Food and Drug Administration (FDA) just released a Safety Alert concerning serious neural tube defects that might arise in babies born to women who took HIV medications that contained the active ingredient Dolutegravir. Neural tube defects are birth defects that can occur early in pregnancy when the spinal cord,

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