Gene variants tied to increased risk of severe COVID-19 disease

October 15, 2020 – SARS-CoV-2 and its resulting disease, Covid-19 disease, is (still) rattling the world. It still remains largely unknown, at this point in time, which are the infected individuals who fall very seriously, even fatally, ill with Covid-19 disease. Of course,

Read more ›

Tags: , , , , , , , , , , , , ,

Increased Risk Of Aneurysms And Artery Dissections With VEGF Inhibitors

August 26 2020 –  Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF)  is a signal protein produced by cells that stimulates the formation of blood vessels. VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot growth factors.

Read more ›

Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Study looks at genetic background of healthy people who develop severe Covid-19 illness

June 13, 2020 – To help disentangle the secrets of Covid-19 disease, researchers are sequencing the DNA of young grown-ups and children who suffer from extreme Covid-19 disease ailments in spite of having no hidden clinical issues. The scientists are searching for hereditary genetic risk factors that could put certain people at high danger of getting seriously sick from the novel coronavirus,

Read more ›

Tags: , , , , , , , ,

Diagnoses for children with rare genetic diseases by 3-D facial scans

June 07, 2020 – Most children with rare genetic diseases spend years undergoing medical tests and waiting for a diagnosis—a long, exhausting process that takes its toll on children and their families. Almost half of these children never get a definitive diagnosis.

In a new and exciting development,

Read more ›

Tags: , , , , , ,

Host factors may influence Covid-19 severity more than viral genetic variation

May 22, 2020 – Host factors (i.e., disease phenotypes and/or predispositions) instead of viral genetic variation seem to impact more on sickness severity among Covid-19 patients, as indicated by an investigation from China. Scientists in Shanghai analyzed clinical, atomic, and immunological information from in excess of 300 individuals with affirmed Covid-19.

Read more ›

Tags: , , , , , , , , , , , , , , , ,

Abdominal aortic aneurysm: Genetic scoring can identify more men at risk

May 07, 2020 – Abdominal aortic aneurysm (AAA) is a localized enlargement of the abdominal aorta such that the diameter is greater than 3 cm or more than 50% larger than normal. AAAs usually cause no symptoms, except during rupture. 

Read more ›

Tags: , , , , , , , , , ,

Besides the now approved remdesivir: Emerging options to treat Covid-19

May 03, 2020 –  The world is desperate in the search for a treatment or better yet a vaccine in the Covid-19 pandemic. Slowly, there are some options emerging at least for the treatment of seriously ill Covid-19 patients. First of all,  the American Food and Drug Administration just issued an emergency use authorization (EUA) for the investigational antiviral drug remdesivir for the treatment of suspected or laboratory-confirmed COVID-19 in adults and children hospitalized with severe disease.

Read more ›

Tags: , , , , , , , , , , , , , , , , ,

Could DNA testing help the most seriously affected Covid-19 patients?

April 28, 2020 – Coronavirus disease 2019 (Covid-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was first identified in December 2019 in Wuhan, the capital of China’s Hubei province,

Read more ›

Tags: , , , , , , , , , , , , , ,

Klotho’s role in some patients with Alzheimer’s disease revealed?

April 24, 2020 – The klotho gene is named after the fanciful Greek goddess of destiny Clotho who turns the string of life known to be related with longer life and improved cognizance. In modern biology, allelic variants of the klotho gene in fact have been associated with long life span.

Read more ›

Tags: , , , , , , , ,

First therapy for children with debilitating NF-1 approved in the USA

April 12, 2020 – The human genetic disease neurofibromatosis type 1 (NF-1) is a complex multi-system disorder caused by the mutation of a gene  (NF1 gene) on chromosome 17 that is responsible for production of a protein called neurofibromin which is needed for normal function in many human cell types.

Read more ›

Tags: , , , , , , , , , , , , , , ,

thasso: conditions

thasso: newest tweets

thasso: recent comments

View my Flipboard Magazine.

thasso: categories

thasso: archives

thasso: simple chat

You must be a registered user to participate in this chat.

  • New COVID-19 related genes—helpful and harmful—found in massive screen October 26, 2020
    Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus.
  • Genetic predisposition to increased weight is protective for breast and prostate cancer October 26, 2020
    Although a recent campaign by Cancer Research UK emphasized obesity as a risk factor for cancer on par with smoking, the scientific literature on the relationship between increased weight and cancer risk is not so clear. In a new analysis, researchers from Brunel University London found that increasing weight is causally protective for breast and […]
  • Insights into the genetic architecture of penicillin allergy October 26, 2020
    Researchers announce the first robust evidence for the role of the major histocompatibility complex gene HLA-B in penicillin allergy. To identify genetic risk factors for penicillin allergy, the international team of researchers harnessed self-reported data and the electronic health records of more than 600,000 people, as well as replicating their findings in two independent research […]
  • Breast cancer risk and disease-causing mutations in women over age 65 October 26, 2020
    Women with the onset of breast cancer over age 65 often do not qualify for genetic testing, yet little is known about the frequency of disease-causing mutations in breast cancer predisposition genes in this population. In a new study, researchers investigated the prevalence of disease-causing variants in established breast cancer predisposition genes and estimated the […]
  • Cell-free DNA provides a dynamic window into health October 26, 2020
    Short fragments of cell-free DNA (cfDNA) that circulate in blood, urine, and other biofluids can offer an information-rich window into human physiology and disease. By looking at the methylation markers of cfDNA, researchers can identify the tissue from which the DNA came. A new study used this method to monitor infectious and immune-related diseases, including […]
  • 3D printing the first ever biomimetic tongue surface October 26, 2020
    Scientists have created synthetic soft surfaces with tongue-like textures for the first time using 3D printing, opening new possibilities for testing oral processing properties of food, nutritional technologies, pharmaceutics and dry mouth therapies.
  • Surprised researchers: Number of leopards in northern China on the rise October 26, 2020
    Most of the world's leopards are endangered and generally, the number of these shy and stunning cats is decreasing. However, according to a recent study by a researcher from University of Copenhagen and colleagues from China, leopard populations in northern China are on the mend. Discover why below.
  • Powering the future: new insights into how alkali-metal doped flexible solar cells work October 26, 2020
    A group of scientists from Korea has discovered that the amount of alkali metal introduced into crystals of flexible thin-film solar cells influences the path that charge carriers take to traverse between electrodes, thereby affecting the light-to-electricity conversion efficiency of the solar cell. Given the immense application potential that such solar cells have today, this […]
  • Scientists establish NanDeSyn Database to support international cooperation on industrial microalgae October 26, 2020
    To promote resource sharing and research cooperation for the synthetic biology and molecular breeding of industrial oil-producing microalgae, an international team led by Single-Cell Center (SCC), Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS), has released the "NanDeSyn Database" (http://www.nandesyn.org).
  • A heart-breast cancer-on-a-chip monitoring system October 26, 2020
    Dual-organ system enables the measurement of cardiac toxicity arising from breast cancer chemotherapy. A collaborative team, which includes a group from the Terasaki Institute for Biomedical Innovation, has developed an organs-on-a-chip system that more widely examines the responses of breast cancer and heart tissues to therapeutic breast cancer drugs.
Top