the glocalized network in theragenomic and personalized medicine and the genetics of individual patients safety of drugs
April 19, 2025 – Orofacial clefts (i.e., cleft lip and cleft palate) are among the most common birth defects, occurring in about one in 1,050 births in the United States, however, they are similarly frequent all over the world with …
Orofacial clefts: Can genetic variants reveal how they arise? Read more »
Aptil 12, 2025 – Theragenomic medicine is an emerging interdisciplinary field that integrates genomic science with therapeutic practice to enhance drug safety and efficacy on an individualized basis. It encompasses the study of how genetic variations impact both the beneficial …
Is there a transformative role of AI in theragenomic medicine? Read more »
April 05, 2025 – Researchers have discovered race-associated molecular differences in tumors that may impact the way patients with pancreatic cancer respond to immunotherapies. The findings, which were recently published in the journal Cancer Research Communications, reinforce the need to …
March 25, 2025 – There are more than 10’000 rare genetic diseases, of which about three-quarters affect children. Overall, rare diseases are becoming increasingly common, affecting about 300 million people globally. One in three children with a rare disease will …
Do global efforts enhance clinical care for children with rare genetic diseases? Read more »
March 20, 2025 – Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide, with approximately 20% of patients presenting with metastatic disease at the time of diagnosis. Despite the cancer’s long progression time, often 5–10 years, …
Does AI unlock genetic keys to improve colorectal cancer survival? Read more »
March 10, 2025 – Does a gene variant shield against the COPA syndrome, a devastating inherited disease? The COPA syndrome is a recently described autosomal dominant inborn error of immunity characterized by high titer autoantibodies and interstitial lung disease, with many …
Does the gene variant HAQ-STING shield against the COPA syndrome? Read more »
March 07, 2025 – On January 30, 2025, the U.S. Food and Drug Administration (FDA) approved Journavx (Suzetrigine), 50 milligram oral tablets, a first-in-class non-opioid analgesic, to treat moderate to severe acute pain in adults. Journavx (Suzetrigine) reduces pain by targeting a …
Journavx (Suzetrigine): Non-Opioid Pain Treatment Appoved by FDA Read more »
March 30, 2025 – A new study from Queen Mary University of London found that 9% of all reported adverse drug reactions (ADRs) reported to the UK medicines regulator are associated with medications where side effect risk is partly dependent …
February 20, 2025 – Black patients with metastatic breast cancer (mBC) showed distinct genomic profiles, including higher rates of specific genetic variants, compared with White patients. Despite equal incidence of PIK3CA alterations, women of color (“black patients”) were significantly less …
Treatment disparity in mBC between women of color and white women Read more »
February 11, 2025 – The MAO-A gene, popularly nicknamed the “warrior gene,” produces the enzyme monoamine oxidase A (MAO-A). It breaks down monoamine neurotransmitters (such as dopamine, epinephrine, and serotonin) through oxidation. Thus, mutations in the MAO-A gene can directly …
The Influence of the MAO-A Gene On Your Personality Read more »