Blog Archives

Coffee Drinking, Genetic Variation, and Mortality

July 07, 2018 – A very recent paper by Loftfield E. et al., published online in JAMA Intern. Med. on July 02, looked at the association of coffee drinking with mortality by genetic variation in caffeine metabolism.

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Direct-to-Consumer Genetic Testing: Are Patients Ready?

March 31, 2018 – Are patients ready for direct-to-consumer genetic testing?  This was the very important and central question that came up in the article by Matt Smith on Medscape, published March 29, 2018.

Since thasso is all about theragenomic and personalized medicine  and individualized drug safety (i.e.

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Placebo: A veritable treatment option

February 11, 2018 – Long after cancer treatment ends, many patients continue to deal with one particular symptom that refuses to go away: fatigue. In a new study, researchers have found that the power of placebos, even when fully disclosed to patients, might be harnessed to reduce fatigue in cancer survivors.

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Infidelity: Genetic Factors Link To Cheating

January 05, 2017 – Most don’t do it over the holiday season. Coming January however, they resume what they do and what in many cases is catastrophic for their relationships, marriages, children, and relatives as well: people cheat. At least for bed-hopping women, their infidel behaviour may, at least,

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Placebomics: Where placebo and genetics meet

December 01, 2017 – The placebome is a new game in town. That is where genetics and the placebo effect meet. The underlying discipline of study may well be “placebomics”, fitting genetics and the uniquely complex phenotype “Placebo Effect” into the -omics age of things.

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SEMA4D gene variant quadruples obesity risk in individuals of African descent

March 26, 2017 – There is ample evidence that the burden of obesity is not the same across ethnic groups. While diet and lifestyle play a large role in determining body weight, there is also a heritable component. Unfortunately,  most prior studies that have evaluated the role of genes in obesity have looked mostly at people of European or Asian descent,

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Some practical thoughts about suicide: Before jumping, you should consult your genes

January 21, 2017 –There are roughly one million suicides worldwide annually, corresponding to an estimated yearly mortality rate of 14.5 deaths per 100,000 people in the general population. In Europe, suicide represents the second leading cause of mortality in the 14–24 age groups. Suicide constitutes a multifactorial public health issue that involves numerous biological,

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The Apomediary [Patient Expert] and Personalized Medicine: A Commentary

June 22, 2014 – The individuum (i.e., patient) is the phenotype expert on her/his individualized form of proper disease she/he is suffering from. It is not her/his treating physician, it is not a regulatory person concerned with the safety and efficacy of the medication geared towards treating her/his condition,

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  • Researchers identify new gene mutation in familial thyroid cancers November 20, 2019
    Researchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid cancer. Dr. Darrin Bann, an otolaryngology resident at the College of Medicine and lead author of the study, said that this mutation is the first and only mutation associated with familial thyroid cancer to be […]
  • Researchers develop new database of druggable fusion targets November 20, 2019
    When sections from two separate genes merge due to various factors, such as translocation or splicing, the hybrid that is formed is called a gene fusion. In recent years, it has been discovered that these fusion events play a vital role in the development of cancers and other complex diseases. However, there are very few […]
  • Early results of CRISPR gene-editing treatment shows promise in first human trials November 20, 2019
    Officials from Vertex Pharmaceuticals and CRISPR Therapeutics have announced that preliminary results from testing CRISPR gene-editing treatment in human patients with blood disorders show promise thus far. The joint project between the two firms is taking place at one location in Europe and another in the United States. The results have been posted on the […]
  • Whole-genome sequencing analysis to find more exact biomarkers November 20, 2019
    A new study from Uppsala University shows that whole-genome sequencing increases the precision of genetic studies, which in turn can improve our understanding of how to use biomarkers to discover disease. The results are published in the scientific journal Scientific Reports.
  • Complex organ models grown in the lab November 19, 2019
    Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.
  • New study confirms American children and teens are consuming significantly less sugary drinks November 21, 2019
    According to a new study in the American Journal of Preventive Medicine, published by Elsevier, the share of children and adolescents consuming sugar-sweetened beverages (SSBs) and the calories they consume from SSBs declined significantly between 2003 and 2014.
  • New Alzheimer risk gene discovered November 21, 2019
    A new paper in the Journal of Neuropathology & Experimental Neurology finds a gene that may help explain a large part of the genetic risk for developing Alzheimer disease.
  • New type of e-cigarette vaping injury described in CMAJ November 21, 2019
    A research case report describing lung injury related to e-cigarette use in a 17-year-old Canadian may be the first documented case of a new form of damage from vaping products. The article, published in CMAJ (Canadian Medical Association Journal) provides new evidence on forms of lung injury that can result from vaping.
  • CUHK Faculty of Engineering develops novel imaging approach November 21, 2019
    By combining a compressive sensing algorithm with a digital holographic microscope, Prof. Shih-Chi CHEN of the Department of Mechanical and Automation Engineering, Faculty of Engineering, The Chinese University of Hong Kong (CUHK) and his research team have developed a high-speed imaging method. The new approach is able to produce two-photon microscopy images of a 3D […]
  • Cybershoppers make better buying decisions on PCs than phones -- Ben-Gurion U. researchers November 21, 2019
    This is the first study that differentiates between screen size and information reduction, which are often mixed up. The findings will be presented next month at the International Conference on Information Systems, the top academic conference in the field.
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