Blog Archives

The phenotype broker: Blockchain and patient phenotype

July 26, 2019 – “Blockchains for secure digitized medicine”. This is the title of a very interesting and important article in the Journal of Personalised Medine (JPM) as of May 28, 2019.

Blockchain as an emerging technology (particularly around the hype on Bitcoins) has been gaining in popularity,

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Where portrait photos meet genetics and AI

June 13, 2019 – This is simply fascinating stuff. Researchers are testing neural networks that automatically combine portrait photos with genetic and phenotypic patient data in order to obtain definitive diagnosis of hereditary rare diseases, all with the help of artificial intelligence (AI).  

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New gene variants in depression

May 13, 2018 – Researchers have uncovered 17 genetic variants linked to different depression-related phenotypes in a large genome-wide association study, including variants near genes involved in neurotransmission and synapse function.

The first author of the study, David Howard, Center for Clinical Brain Sciences, University of Edinburgh,

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Chinese arrhythmia in traditional medicine

May 04, 2018 – All natural is healthy. This is a common belief for many, particularly when shopping for alternative medicines and dietary supplements. For many, however, the contrary might be fatally true.

As a point in case, new research shows, that substances in Traditional Chinese Medicine  (TCM) can cause severe cardiac arrhythmia. 

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Placebo: A veritable treatment option

February 11, 2018 – Long after cancer treatment ends, many patients continue to deal with one particular symptom that refuses to go away: fatigue. In a new study, researchers have found that the power of placebos, even when fully disclosed to patients, might be harnessed to reduce fatigue in cancer survivors.

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Placebomics: Where placebo and genetics meet

December 01, 2017 – The placebome is a new game in town. That is where genetics and the placebo effect meet. The underlying discipline of study may well be “placebomics”, fitting genetics and the uniquely complex phenotype “Placebo Effect” into the -omics age of things.

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Amish People: Old age because of genetic mutations?

November 20, 2017 – Thanks to old aged Amish people, the first ever anti-ageing genetic mutation(s) have been discovered. According to a study published in the Journal Science Advances revealed a research team from a Northwestern University Feinberg School of Medicine, Chicago, IL, USA that seemingly an Indiana Amish

community holds the (genetic) key to living  about 10% longer.

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Spinal Muscular Atrophy: Single-Dose Gene-Replacement Therapy

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Theragenomic medicine: Accurate treatment response prediction in depressed patients

November 05, 2017 – For some patients knowingly or not knowingly suffering from depression, the upcoming period of the year (i.e., the winter season in the Northern Hemisphere) with grey days and over-porportionally long nights, might be a difficult one. Should such patients enter a antidepressant treatment,

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Is there a risk of melanoma with erectile dysfunction drugs?

November 01, 2017 – According to the watch list of the American Food & Drug Administration (FDA) for drugs with possible safety issues from January to March 2016,

the FDA was looking at the possible link between various drugs in the phosphodiesterase-5 (PDE-5) inhibitors class and melanoma as a serious adverse effect.

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  • Researchers find genetic links to child obesity across diverse ethnic groups August 22, 2019
    An international team of researchers who analyzed data across multiple ethnicities has produced the largest genetic study to date associated with common childhood obesity. The Early Growth Genetics (EGG) Consortium discovered a robust new signal, fine-mapped previously reported genetic variants, and added to evidence that genetic influences on obesity operate across the lifespan.
  • Researchers develop model to personalize radiation treatment August 22, 2019
    A personalized approach to cancer treatment has become more common over the last several decades, with numerous targeted drugs approved to treat particular tumor types with specific mutations or patterns. However, this same personalized strategy has not translated to radiation therapy, and a one-size-fits-all approach for most patients is still common practice. Moffitt Cancer Center […]
  • How our genes and environment influence BMI and height August 22, 2019
    Environmental conditions influence our body mass index (BMI) by increasing or decreasing the effect of inherited genetic variations, University of Queensland researchers have discovered.
  • Genetic testing and family tree research are revealing painful family secrets, research says August 22, 2019
    Genealogical research and genetic testing are revealing skeletons in family closets and causing rifts among members, a new study shows.
  • Researchers use single-cell sequencing to get a better look at human embryo implantation August 22, 2019
    A team of researchers affiliated with multiple institutions in China has used single-cell sequencing to learn more about the human embryo during implantation in the uterus. In their paper published in the journal Nature, the group describes sequencing thousands of human embryo cells from before, during and after implantation, and what they learned from it.
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