May 08, 2022 – Umbralisib (Ukoniq) is a medication for the treatment of marginal zone lymphoma (MZL) and follicular lymphoma (FL). Umbralisib (Ukoniq) inhibits multiple kinases. In biochemical and cell-based assays, Umbralisib inhibited PI3Kδ and casein kinase CK1ε. PI3Kδ is expressed in …

Umbralisib (Ukoniq): Drug recall because increased risk of patient death Read more »

April 30, 2022 – In a very recent report published in PLoS Genetics  by Dr. Verma of the Corporal Michael Crescenz VA Medical Center in Philadelphia, Pennsylvania, US, and colleagues, new data from the Veterans Affairs Million Veteran Program (MVP) has …

Genetic links revealed between severe COVID-19 and other diseases Read more »

April 10, 2022 – Sotrovimab, sold under the brand name Xevudy, is a monoclonal antibody that was available under emergency use authorization (EUA) from the FDA and similar urgency authorisations from several drug regulatory agencies worldwide for the treatment of patients …

SARS-CoV-2 Delta Variant: Resistance Mutations after Sotrovimab Use Read more »

March 10, 2022 – In a new report distributed in “Circulation: Genomic and Precision”, scientists showed that as while numerous African Americans, particularly those with a high African Family extent, have a good lipid profile, they are at a higher …

Genetic variations and social health determinants may lead to higher risk for diabetes in individuals with high African heritage Read more »

February 20, 2022 – Genomics data are currently being produced at unprecedented rates, resulting in increased knowledge discovery and submission to public data repositories. Hopefully, these data assemblies will one day serve the advanced implementation of theragenomics and personalized medicine …

AGMP: The African Genomic Medicine Portal Read more »

February 02, 2022 – The search to better understand the tremendous range of responses to infection with the SARS-CoV-2 virus, from symptom free to critically or even fatally ill has uncovered in some of the sickest patients a handful of rare …

Genetic variants in extremely ill COVID patients explain how fatally sick people may get Read more »

January 30, 2022 – This was retrospectively seen information just in time for the holiday season. A new study in Scientific Reports on December 13 2021 comforts people who like to eat lots of black chocolate and to drink their coffee black …

What do genes tell about black coffee and chocolate? Read more »

October 28 , 2021 – One of the most interessant and still unresolved question in connection with Covid-19 disease is the fact that some patients develop a heavy, if not fatal forms of Covid-19 disease after their infection with SARS-CoV-2 while …

Drivers of severe Covid-19 disease in patients under 50 without comorbidities Read more »

October 18, 2021 – It is still unclear how exactly SARS-CoV-2 passed on to humans. How did the coronavirus pandemic, which is still affecting everyday life and coexistence around the world, even begin? Almost two years after the virus first …

SARS-CoV-2-like RBD allowing ACE2-mediated entry into human cells from bats of Indochinese peninsula Read more »

September 19, 2021 – An article like this one goes right to my bones. Having a lifelong affinity to history of things, not only in my field of theragenomic medicine, but also in many other issues like politics, humanity, science, and …

Coronavirus epidemics first hit more than 21’000 years ago Read more »