the glocalized network in theragenomic and personalized medicine and the genetics of individual patients safety of drugs
March 18, 2023 – Valtrex (Valacyclovir) is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. It is a prodrug, …
Canada: DRESS Syndrome associated with Valtrex (Valacyclovir) Read more »
March 01, 2023 – The gene APOE codes for apolipoprotein E (Apo-E), a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in the Alzheimer’s disease and cardiovascular diseases. Recently, researchers at Stanford University …
APOE Missense Variant Linked to Increased Alzheimer’s Disease Risk in African Americans Read more »
February 07, 2023 –Â CRISPR is a genetic engineering technique by which the genomes of living organisms may be modified. It is based on a simplified version of the bacterial CRISPR–Cas9 antiviral defense system. By delivering the Cas9 nuclease complexed with …
CRISPR: Does it help diseased plants and humans alike? Read more »
January 08, 2023 –Â In precision and/or targeted medicine of today, physicians typically start out with the determination of the patients phenotypic expression of a disease (i.e., establish a clinical finding) and then go on into finding out the patients genetic …
Genomic variants traced forward to genetic disorders: A new approach? Read more »
December 22, 2022 – Are the many effects of ketamine clinically manageable? For treating clinicians and their patients receiving ketamine for quite a number of indications such as starting and maintaining general anesthesia, some forms of chronic pain relief, and some types …
Ketamine, Depression, Addiction: Is it a Cure, a Cause or a Vicious Cycle? Read more »
December 11, 2022 – We’re all familiar with the five senses that allow us to experience our surroundings, namely sight, hearing, smell, taste, and touch. However, equally important but much less well known is the so called Sixth Sense. Sixth sense …
The sixth sense: Are there genes associated with it? Read more »
November 27, 2022 – About 3.5–5.9% of the world population are affected by a rare diseases. For Africa alone, this winds up to around 50 million possibly affected people, representing a large community of individuals and families in need of diagnostics …
Including Africa in the research on rare genetic diseases: A must! Read more »
November 20, 2022 – The genetics of drug side-effects. Some 95% of people have a gene variant that affects their response to at least one drug. Treating physicians, clinical researchers, and affected patients know all to well the serious problems that …
Is there pre-emptive genotyping to avoid adverse drug effects (ADRs)? Read more »
November 10, 2022 – Drug addiction is a huge social problem of our todays societies. The problem does not only exist in the USA, but in other countries worldwide as well, with enormous numbers of victims due to alcoholism, smoking, …
29. October 2022 –Â A first clinical guideline on Schaaf-Yang syndrome for professionals and families has been created. Improving knowledge of Schaaf-Yang syndrome (SYS), an ultra-rare disease caused by mutations in the MAGEL2 gene, is the aim of this first clinical …
The extremely rare Schaaf-Yang Syndrome and the MAGEL2 gene Read more »