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Therapies that promote progressive multifocal leukoencephalopathy (PML)

August 23, 2019 – Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal viral disease characterized by progressive damage or inflammation of the white matter of the brain at multiple locations (i.e., multifocal). It is caused by the JC virus,

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Fingolimod (Gilenya): Warning about rare cases of progressive multifocal leukoencephalopathy (PML)

August 06, 1015 – The American Food and Drug Administration (FDA) has just issued a warning that a case of definite progressive multifocal leukoencephalopathy (PML) and a case of probable PML have been reported in patients taking Fingolimod (Gilenya) for multiple sclerosis (MS).

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Theragenomic medicine: First case of fumarate-linked progressive multifocal leukoencephalopathy (PML) in nonlymphopenic patient

April 11, 2015 – Dutch clinicians report what they believe is the first case of progressive multifocal leukoencephalopathy (PML) after treatment with compounded dimethyl fumarate (DMF) in a patient without severe lymphocytopenia. This situation was “previously thought to be unlikely,” Dennis Nieuwkamp,

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First Case of Progressive Multifocal Leukoencephalopathy (PML) in a Patient Treated with Dimethyl Fumarate [Tecfidera]

November 7, 1014 –  This report originates from the meeting highlights from the Pharmacovigilance Risk Assessment Committee (PRAC) on 3-6 November 2014 at EMA.

At this meeting, the PRAC took note and advised on informing about first case of PML in a patient treated with Tecfidera.

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  • One size does not fit all: Not all men idolize Western ideals of muscularity April 3, 2020
    UK researchers reported that men in Uganda and Nicaragua were generally less hung up about their body image and cared less about pursuing a muscular physique than British men. The study employed new body-imaging technology and machine learning to understand different cultural attitudes around the drive toward ideals of muscularity. Understanding variation between groups is […]
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    An increased proportion of Indigenous American (IA) ancestry was associated with a greater incidence of HER2-positive breast cancer, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.
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    CNIC scientists have uncovered a new molecular mechanism that determines the identity and expansion of one of the cell types that work as immune sentinels in the body -- the macrophages of the serous cavities.
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    While drylands around the world will expand at an accelerated rate because of future climate change, their average productivity will likely be reduced, according to a new study. These regions, which primarily include savannas, grasslands and shrublands, are important for grazing and non-irrigated croplands. They are also a critical part of the global carbon cycle […]
  • Discovery of life in solid rock deep beneath sea may inspire new search for life on Mars April 2, 2020
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