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Therapies that promote progressive multifocal leukoencephalopathy (PML)

Posted on by by Posted in Adverse Drug Reaction [ADR], Commentary, Thasso Post, Theragenomic Medicine No Comments ↓

August 23, 2019 – Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal viral disease characterized by progressive damage or inflammation of the white matter of the brain at multiple locations (i.e., multifocal). It is caused by the JC virus,

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Ofatumumab (Arzerra) approved for recurrent or progressive chronic lymphocytic leukemia (CLL)

Posted on by by Posted in New Indication Approval, Regulatory Approval, Thasso Post, Theragenomic Medicine No Comments ↓

January 20, 2016 – The American Food and Drug Administration (FDA) just approved Ofatumumab (Arzerra)  Injection for extended treatment of patients who are in complete or partial response after at least two lines of therapy for recurrent or progressive chronic lymphocytic leukemia (CLL). 

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Idelalisib (Zydelig) for three types of blood cancers approved

Posted on by by Posted in New Drug Approval, Targeted Therapy, Thasso Post, Theragenomics No Comments ↓

July 23, 2014 – The U.S. Food and Drug Administration today approved Zydelig (idelalisib) to treat patients with three types of blood cancers.

Zydelig is being granted traditional approval to treat patients whose chronic lymphocytic leukemia (CLL) has returned (relapsed).

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RSS random genetics

  • Researchers identify new gene mutation in familial thyroid cancers November 20, 2019
    Researchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid cancer. Dr. Darrin Bann, an otolaryngology resident at the College of Medicine and lead author of the study, said that this mutation is the first and only mutation associated with familial thyroid cancer to be […]
  • Researchers develop new database of druggable fusion targets November 20, 2019
    When sections from two separate genes merge due to various factors, such as translocation or splicing, the hybrid that is formed is called a gene fusion. In recent years, it has been discovered that these fusion events play a vital role in the development of cancers and other complex diseases. However, there are very few […]
  • Early results of CRISPR gene-editing treatment shows promise in first human trials November 20, 2019
    Officials from Vertex Pharmaceuticals and CRISPR Therapeutics have announced that preliminary results from testing CRISPR gene-editing treatment in human patients with blood disorders show promise thus far. The joint project between the two firms is taking place at one location in Europe and another in the United States. The results have been posted on the […]
  • Whole-genome sequencing analysis to find more exact biomarkers November 20, 2019
    A new study from Uppsala University shows that whole-genome sequencing increases the precision of genetic studies, which in turn can improve our understanding of how to use biomarkers to discover disease. The results are published in the scientific journal Scientific Reports.
  • Complex organ models grown in the lab November 19, 2019
    Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.

RSS random science

  • Outback telescope captures Milky Way center, discovers remnants of dead stars November 20, 2019
    A radio telescope in the Western Australian outback has captured a spectacular new view of the centre of the galaxy in which we live, the Milky Way.The image from the Murchison Widefield Array (MWA) telescope shows what our galaxy would look like if human eyes could see radio waves.
  • Leadership's in the blood for tiny fish November 20, 2019
    Leadership during cooperation runs in the family for tiny fish called Trinidadian guppies, new research shows.
  • Non-invasive microscopy detects activation state and distinguishes between cell types November 20, 2019
    Most analytical methods in biology require invasive procedures to analyze samples, which leads to irreversible changes or even their destruction. Here, researchers from Osaka University develop a non-invasive, label-free optical approach along with statistical tools to reveal immune cell type, cell activation state, and single cell heterogeneity.
  • Living in ethnic enclaves may improve pregnancy outcomes for Asian/Pacific islanders November 20, 2019
    Among Asian/Pacific Islander women living in the United States, those who reside in ethnic enclaves--areas with a high concentration of residents of a similar ancestry--are less likely to have pregnancy or birth complications than those living in other areas, suggests a study by researchers at the National Institutes of Health and other institutions.
  • Study: Young children can learn math skills from intelligent virtual characters November 20, 2019
    A new study examined whether young children's verbal engagement with an onscreen interactive media character could boost their math skills. The study concluded that children's parasocial (that is, one-sided) emotional relationships with the intelligent character and their parasocial interactions (in this case, talking about math with the character) led to quicker, more accurate math responses […]
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