December 28, 2020 – Some 95% of people have gene variants that may negatively affect their response to at least one drug, leading to unexpected or adverse drug reactions (ADRs) or, if unlucky, to a serious, if not fatal, adverse …

Genetics behind some serious adverse drug reactions (SADRs) Read more »

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August 01, 2019 – Post-Traumatic Stress Disorder (PTSD) is a mental disorder that can develop after a person is exposed to a traumatic event, such as sexual assault, warfare, traffic collisions, or other threats on a person’s life. Symptoms may include disturbing …

Risk loci for post-traumatic stress disorder (PTSD) Read more »

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July 26, 2019 – “Blockchains for secure digitized medicine”. This is the title of a very interesting and important article in the Journal of Personalised Medine (JPM) as of May 28, 2019. Blockchain as an emerging technology (particularly around the hype …

The phenotype broker: Blockchain and patient phenotype Read more »

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May 06, 2019 – Dancing, integrally related to music, likely has its origins close to the birth of Homo sapiens. Some researchers for a long time have hypothesized that there are differences in aptitude, propensity, and need for dancing that …

Creative dancing and the genetic predisposition of it Read more »

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Sacco K, Grech G EPMA J 2015;6(1):15 PMID: 26203310 Abstract Breast cancer is a heterogeneous disease that necessitates proper patient classification to direct surgery, pharmacotherapy, and radiotherapy. Despite patients within the same subgroup receiving similar pharmacotherapy, substantial variation in clinical …

Actionable pharmacogenetic markers for prediction and prognosis in breast cancer Read more »

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June 22, 2014 – The individuum (i.e., patient) is the phenotype expert on her/his individualized form of proper disease she/he is suffering from. It is not her/his treating physician, it is not a regulatory person concerned with the safety and …

The Apomediary [Patient Expert] and Personalized Medicine: A Commentary Read more »

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