the new generation glocalized patient network in theragenomic and personalized medicine and individualized drug safety
25 June 2022 – Xalkori (Crizotinib)-related ocular toxicity and severe visual loss are difficult to detect in children. This comes out of a Dear Healthcare Professional Communication (DHPC) letter from the European Medicine Agency (EMA) following it’s June 2022 Pharmacovigilance Risk Assessment …
Xalkori: Ocular Toxicity and Severe Visual Loss in Children Read more »
April 12, 2020 – The human genetic disease neurofibromatosis type 1 (NF-1) is a complex multi-system disorder caused by the mutation of a gene  (NF1 gene) on chromosome 17 that is responsible for production of a protein called neurofibromin which is …
First therapy for children with debilitating NF-1 approved in the USA Read more »
April 23, 2017 – This is a Safety Announcement from April 20, 2017, by the American Food & Drug Administration (FDA) to the fact that FDA further restricts use of prescription codeine pain and cough medicines and tramadol pain medicines in …
Living theragenomics: Dangers of codeine and tramadol medicines in children Read more »
April 04, 2017 –Â Personalized medicine, also referred to as precision medicine, incorporates the individual patient’s characteristics into treatment, rather than relying on population means. Over the past several years, it has become a significant focus for research. Developments in pharmacogenomics, …
Children: Is there personalized medicine for children too? Read more »
September 03, 2016 – This morning, I stumbled upon the headline of a posting on mobihealthnews, entitled “Study finds iPads and games as effective as sedatives to calm pre-op anxiety in children” and starting out with saying “The hypnotic trance …
March 21, 2015 – The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has recently recommended restrictions on the use of codeine-containing medicines for cough and cold in children because of the risk of serious side effects with these medicines, including the risk of breathing …
September 27, 2014 –Â A while ago (August 2012), Â the American Food and Drug Administration (FDA) was assessing and reporting on the (possibly fatal) risks associated with the use of codeine containing medicines in children who are phenotypically members of the …
November 3, 2009 – As we learn from it’s todays announcement, FDA is requiring stronger warnings about an increased risk of lymphoma and other cancers in children and adolescents who are treated with drugs that block tumor necrosis factor. TNF …
Boxed Warning Updated: TNF Blockers and Cancer Risks in Children Read more »
October 30, 2009 – Schizophrenia drugs, increasingly prescribed to children with bipolar disorder and other conditions, can cause youngsters to experience rapid weight gain, according to a new study. Thus, children and adolescents who take the drugs, known as atypical …