Blog Archives

Three idiopathic pulmonary fibrosis (IPF)-associated genes newly identified

March 05, 2020 – Idiopathic pulmonary fibrosis (IPF) is a type of chronic scarring lung disease characterized by a progressive and irreversible decline in lung function. Symptoms typically include gradual onset of shortness of breath and a dry cough.

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Degree of African ancestry may influence gene expression levels

January 26, 2020 – Common belief holds that differences in genes (i.e., allelic variants) in combination with differing frequencies of such allelic variants in populations of different ethnic background may explain the differences in the frequency and/or severity of overt diseases in different ethnic groups and/or populations.

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Genetic aspects of globesity: Glocalized or not?

June 25, 2019 – The global obesity epidemic is so far-reaching it now has an overarching name: globesity (obviously derived from global obesity).  Very interesting questions arise in this context such as are there glocalized (global and or local) factors involved in this epidemic.

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Ethnic disparities in the occurrence of prostate cancer

May 10, 2018 – A seemingly higher incidence of prostate cancer and resulting fatalities in African-American men than in European-Amcerican men has been noted for quite some time. New research published in Molecular Oncology may help explain why African American men are at a higher risk of being diagnosed with prostate cancer and a higher risk of dying from the disease compared with European American men.

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Breast Cancer: Performance of prognostic signatures

February 17, 2018 – In a new study, published in JAMA Oncology online on February 15, 2018, a comparison of the performance of 6 prognostic signatures for estrogen receptor (ER) –positive breast cancer was performed in a secondary analysis of a randomized clinical trial.

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Gene expression and ethnicity: Does it matter?

December 05, 2017 – We are entering the age of precision medicine, in which diagnosis and therapy decisions for each patient will be based on detailed genetic and molecular fingerprints. Unfortunately, much of the revolutionary work that underpins precision medicine has been conducted on populations of European (Caucasian) descent,

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  • Study identifies pitfall for correcting mutations in human embryos with CRISPR October 29, 2020
    In a paper published today in the journal Cell, scientists describe unexpected, undesirable outcomes after editing genes in human embryos with CRISPR, a genomic editing system.
  • Spread of a novel SARS-CoV-2 variant across Europe in summer 2020 October 29, 2020
    Researchers from Basel and Spain have identified a novel SARS-CoV-2 variant that has spread widely across Europe in recent months, according to an un-peer-reviewed preprint released this week. While there is no evidence of this variant being more dangerous, its spread may give insights into the efficacy of travel policies adopted by European countries during […]
  • New 'epigenetic' clock provides insight into how the human brain ages October 29, 2020
    While our circadian body clock dictates our preferred rhythm of sleep or wakefulness, a relatively new concept—the epigenetic clock—could inform us about how swiftly we age, and how prone we are to diseases of old age.
  • Results of COVID-19 host genetics initiative study announced at ASHG 2020 October 29, 2020
    The COVID-19 pandemic is a global health crisis. Insights into why some people develop more severe symptoms than others and how to better treat the disease are desperately needed. The COVID-19 Host Genetics Initiative was created to study the relationship between variation in the human genome and SARS-CoV-2 infection. This is an ongoing, international, collaborative […]
  • Genetics and the COVID-19 pandemic October 29, 2020
    With the COVID-19 pandemic still raging worldwide, members of the American Society of Human Genetics (ASHG) are working to understand how the virus spreads and infects people, why there is so much variability in susceptibility and severity, and where to look for potential therapeutics. Researchers presented the results of several studies relevant to the current […]
  • Why people with dementia go missing October 29, 2020
    People with dementia are more likely to go missing in areas where road networks are dense, complicated and disordered - according to new research from the University of East Anglia. Researchers studied hundreds of 'missing person' police reports for people with dementia and compared each case to the surrounding road network.They hope their findings could […]
  • An Earth-sized rogue planet discovered in the Milky Way October 29, 2020
    Our Galaxy may be teeming with rogue planets, gravitationally unbound to any star. An international team of scientists, led by Polish astronomers, has announced the discovery of the smallest Earth-sized free-floating planet found to date.
  • Curbing COVID-19 hospitalizations requires attention to construction workers October 29, 2020
    Construction workers, who are disproportionately Hispanic or Latino, have a much higher risk of becoming hospitalized with the novel coronavirus than non-construction workers, according to a new study in JAMA Network Open.
  • Some COVID-19 "long haulers" experience lasting skin problems October 29, 2020
    Some patients with COVID-19 have persistent skin-related symptoms long after their initial infection has cleared, according to a new analysis. The findings, presented at the 29th Congress of the European Academy of Dermatology and Venereology by investigators at Massachusetts General Hospital, point to another burden experienced by so-called "long haulers" who get better but don't […]
  • Early results from DETECT study suggest fitness trackers can predict COVID-19 infections October 29, 2020
    Examining data from the first six weeks of their landmark DETECT study, a team of scientists from the Scripps Research Translational Institute sees encouraging signs that wearable fitness devices can improve public health efforts to control COVID-19.
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