November 10, 2022 – Drug addiction is a huge social problem of our todays societies. The problem does not only exist in the USA, but in other countries worldwide as well, with enormous numbers of victims due to alcoholism, smoking, …

Do genes affect our risk for addiction? Read more »

29 July 2022 – This is a mind-boggling article out of the MedicalXpress news portal, which I present here almost original and unedided. So, all the credentials go to the authors at MedicalXpress. Here the article: The Rady Children’s Institute for …

Is there rapid management of 500 (rare) genetic diseases? Read more »

June 23, 2022 – Expansion of pharmacogenetics education agreed as part of lawsuit settlement. This has just been the headline objective of one of the latest blogs from the PharmGKB blogspot, an NIH-funded resource (database) that provides information about how …

Real world theragenomics and personalised medicine Read more »

May 01, 2021 – Fish oil supplements are a billion-dollar industry built on a foundation of a huge array of studies, sometimes with contra-dictionary outcomes, indicating a reduction of serum triglycerides (TAGs) but somewhat mixed effects on other circulating cardiovascular biomarkers. Genetic …

Fish oil: Your genotype may tell you to take it or not Read more »

December 28, 2020 – Some 95% of people have gene variants that may negatively affect their response to at least one drug, leading to unexpected or adverse drug reactions (ADRs) or, if unlucky, to a serious, if not fatal, adverse …

Genetics behind some serious adverse drug reactions (SADRs) Read more »

January 26, 2020 – An effort to map thousends of genomes across Asia has certainly the potential to find novel gene variants affecting disease and responses to drugs, and to reveal the complex origins of Asian populations. In a pilot …

The diversity of Asian genomes Read more »

August 06, 1015 – The American Food and Drug Administration (FDA) has just issued a warning that a case of definite progressive multifocal leukoencephalopathy (PML) and a case of probable PML have been reported in patients taking Fingolimod (Gilenya) for …

Fingolimod (Gilenya): Warning about rare cases of progressive multifocal leukoencephalopathy (PML) Read more »

February 8, 2015 – The American Food and Drug Administration (FDA) has granted accelerated approval to Palbociclib (Ibrance) to treat advanced (metastatic) breast cancer.  The FDA granted Ibrance breakthrough therapy designation because the sponsor demonstrated through preliminary clinical evidence that the …

Theragenomic Medicine: Palbociclib (Ibrance) approved for postmenopausal women with advanced (metastatic) breast cancer Read more »

November 20, 2014 –  Recent research has addressed the clinically strikingly wide variation among patients in plasma levels of Atorvastatin (Lipitor) and Rosuvastatin (Crestor), even with consistent dosing. This research proposes that the phenomenon is likely related to gene variants …

Theragenomic Medicine: Genotyping Might Cut Muscle-Pain Risk with Statin Drugs Read more »

October 05, 2014 – To strengthen the safety of medical devices, the U.S. Food and Drug Administration has finalised and released recommendations to manufacturers for managing cybersecurity risks to better protect patient health and information. The final guidance, titled “Content …

Steps to strengthen cybersecurity of medical devices Read more »