February 27, 2020 – Thiopurines are important antimetabolite drugs, which make up a critical part of curative treatment for ALL. Genetic variations can directly influence drug toxicity and effectiveness of thiopurines. Researchers at St. Jude and elsewhere previously identified NUDT15 …

Genetic variants of the NUDT15 gene drive toxicity in leukemia therapy Read more »

February 20, 2020 – Traditional cardiovascular risk factors often assessed in an annual physical, such as blood pressure, cholesterol levels, diabetes, and smoking status, may at least be as valuable in predicting who will develop coronary heart disease (CHD) as …

Heart disease prediction by traditional risk factors as good as with an exhaustive genetic test Read more »

January 31, 2018 – Chocolate and the sweet taste receptor gene TAS1R2 may make the life of some obese children and adolescents rather difficult in that genetic variations in TAS1R2 appear related to chocolate powder and dietary fiber intake in these …

Chocolate and the sweet taste receptor gene TAS1R2 Read more »

March 19, 2017 – The evolutionary reasons for variation in nose shape across human populations have been subject to continuing debate. An import function of the nose and nasal cavity is to condition inspired air before it reaches the lower …

What your nose shape might tell you Read more »