January 26, 2019 – Pharmacogenomic approaches are increasingly revealing newly identified genes and genetic variants that are at the base of remarkable inter-individual pharmacokinetic and pharmacodynamic variation of novel direct oral anticoagulants (DOAC). Lately, DOACs have shown an upward prescribing trend due …

Direct Oral Anticoagulants (DOAC): Newly Identified Genes and Genetic Variants Read more »

  February 08, 2017 – Genetic predisposition may go in both ways, the positive and the negative. Usually, when we talk about genetic predisposition, there is an immediate association with some unwanted reactions of individuals towards drugs (e.g., abacavir-induced hypersensitivity …

Genetic predisposition and sweating: Most Koreans don’t have to wear deodorants Read more »

February 04, 2016 – Genetic variations on a stretch of chromosome may predict responsiveness among patients with bipolar disorder to the mood stabilizing drug lithium (multiple brands), a genome-wide analysis by an international consortium shows. Lithium is a first-line treatment for …

Genetic Variants Predict Lithium Response in Bipolar Disorder Read more »