March 27, 2024 – Lyrica (Pregabalin) is a drug from the group of gabapentinoids and is an anticonvulsant active ingredient. It has been approved throughout the EU since 2004 for the treatment of neuropathic pain, epilepsy and generalized anxiety disorder. …

Lyrica (Pregabalin): Thousands of deaths? Read more »

December 22, 2022 – Are the many effects of ketamine clinically manageable? For treating clinicians and their patients receiving ketamine for quite a number of indications such as starting and maintaining general anesthesia, some forms of chronic pain relief, and some types …

Ketamine, Depression, Addiction: Is it a Cure, a Cause or a Vicious Cycle? Read more »

January 26, 2019 – Pharmacogenomic approaches are increasingly revealing newly identified genes and genetic variants that are at the base of remarkable inter-individual pharmacokinetic and pharmacodynamic variation of novel direct oral anticoagulants (DOAC). Lately, DOACs have shown an upward prescribing trend due …

Direct Oral Anticoagulants (DOAC): Newly Identified Genes and Genetic Variants Read more »

September 01, 2016 – This is what we learned this morning and sadly, the issue of opioids use in the population along with its fatal outcomes seems never to stop.  The American Food & Drug Asministation (FDA) requires, according to a …

The opioid epidemic: Is there a never ending sad story? Read more »

May 24, 2014 – There is a ever rising number of drugs that can be risky when taken with grapefruit due to the an increase of new medications that share some critical metabolic pathways on a particular drug metabolising enzyme …

Theragenomic Community Wisdom: Grapefruit Can Interact With Drugs. Better Be Safe Than Sorry. Read more »

November 17, 2009 – Today, the US Food and Drug Administration (FDA) informed on new data showing that the proton pump inhibitor (PPI) Omeprazole [Prilosec] or [Prilosec OTC] reduces the anti-blood clotting effect of Clopidogrel [Plavix] by almost half when …

Avoid Coadministration of Clopidogrel [Plavix] and Omeprazole [Prilosec] or Esomeprazole [Nexium] Read more »