January 26, 2019 – Pharmacogenomic approaches are increasingly revealing newly identified genes and genetic variants that are at the base of remarkable inter-individual pharmacokinetic and pharmacodynamic variation of novel direct oral anticoagulants (DOAC). Lately, DOACs have shown an upward prescribing trend due …

Direct Oral Anticoagulants (DOAC): Newly Identified Genes and Genetic Variants Read more »

September 01, 2016 – This is what we learned this morning and sadly, the issue of opioids use in the population along with its fatal outcomes seems never to stop.  The American Food & Drug Asministation (FDA) requires, according to a …

The opioid epidemic: Is there a never ending sad story? Read more »

May 24, 2014 – There is a ever rising number of drugs that can be risky when taken with grapefruit due to the an increase of new medications that share some critical metabolic pathways on a particular drug metabolising enzyme …

Theragenomic Community Wisdom: Grapefruit Can Interact With Drugs. Better Be Safe Than Sorry. Read more »

November 17, 2009 – Today, the US Food and Drug Administration (FDA) informed on new data showing that the proton pump inhibitor (PPI) Omeprazole [Prilosec] or [Prilosec OTC] reduces the anti-blood clotting effect of Clopidogrel [Plavix] by almost half when …

Avoid Coadministration of Clopidogrel [Plavix] and Omeprazole [Prilosec] or Esomeprazole [Nexium] Read more »