March 31, 2018 – Are patients ready for direct-to-consumer genetic testing?  This was the very important and central question that came up in the article by Matt Smith on Medscape, published March 29, 2018. Since thasso is all about theragenomic …

Direct-to-Consumer Genetic Testing: Are Patients Ready? Read more »

February 17, 2018 – In a new study, published in JAMA Oncology online on February 15, 2018, a comparison of the performance of 6 prognostic signatures for estrogen receptor (ER) –positive breast cancer was performed in a secondary analysis of a randomized …

Breast Cancer: Performance of prognostic signatures Read more »

February 11, 2018 – Long after cancer treatment ends, many patients continue to deal with one particular symptom that refuses to go away: fatigue. In a new study, researchers have found that the power of placebos, even when fully disclosed to …

Placebo: A veritable treatment option Read more »

January 13, 2018 – The American Food and Drug Administration (FDA) has just approved the first treatment for breast cancer with a certain inherited genetic mutation. At first glance, this announcement may be just one in the series of announcements by the …

Olaparib Tablets (Lynparza): For breast cancer with BRCA gene mutation Read more »

January 01, 2018 – Antidepressants are not at all a “one-size-fits-all pill”. Predicting treatment response in depression in order to get the “right” treatment, efficacious and adverse effects free at the same time, is still a huge challenge. Inter-individual variability …

From mice and men: Predicting anti-depressant response Read more »

Dezember 21, 2017 – Erdheim–Chester disease ((ECD), also known as Erdheim–Chester syndrome or polyostotic sclerosing histiocytosis) is a form of a bone marrow borne blood cancer. It is a rare disease characterized by the abnormal multiplication of a specific type …

Vemurafenib (Zelboraf) for BRAF V600E positive Erdheim-Chester Disease (ECD) Read more »

 December 16, 2017 – As recent as of December 14, 2017, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion, recommending the granting of a conditional marketing authorisation for the …

X-linked Hypophosphatemia: Burosumab (Crysvita) to the rescue Read more »

December 05, 2017 – We are entering the age of precision medicine, in which diagnosis and therapy decisions for each patient will be based on detailed genetic and molecular fingerprints. Unfortunately, much of the revolutionary work that underpins precision medicine has …

Gene expression and ethnicity: Does it matter? Read more »

November 24, 2017 – New research indicates that one-size treatment for one form of blood cancer likely does not fit all, particularly when it comes to ethnic differences of patients.  Thus, African-American men are three times more likely to be …

Cancer is not like cancer: Ethnic background matters Read more »

November 05, 2017 – For some patients knowingly or not knowingly suffering from depression, the upcoming period of the year (i.e., the winter season in the Northern Hemisphere) with grey days and over-porportionally long nights, might be a difficult one. Should …

Theragenomic medicine: Accurate treatment response prediction in depressed patients Read more »