the glocalized network in theragenomic and personalized medicine and the genetics of individual patients safety of drugs
May 05, 2018 – The American Food and Drug Administration (FDA) just approved the combination of Dabrafenib (Tafinlar)/Trametinib (Mekinist) to be administered together for the treatment of anaplastic thyroid cancer (ATC) that cannot be removed by surgery or has …
Dabrafenib/Trametinib-Combo approved for BRAF-positive anaplastic thyroid cancer Read more »
January 13, 2018 – The American Food and Drug Administration (FDA) has just approved the first treatment for breast cancer with a certain inherited genetic mutation. At first glance, this announcement may be just one in the series of announcements by the …
Olaparib Tablets (Lynparza): For breast cancer with BRCA gene mutation Read more »
Dezember 21, 2017 – Erdheim–Chester disease ((ECD), also known as Erdheim–Chester syndrome or polyostotic sclerosing histiocytosis) is a form of a bone marrow borne blood cancer. It is a rare disease characterized by the abnormal multiplication of a specific type …
Vemurafenib (Zelboraf) for BRAF V600E positive Erdheim-Chester Disease (ECD) Read more »
May 24, 2917 – The American Food & Drug Administration (FDA) just approved a major extension of the clinical indications for Pembrolizumab (Keytruda). For the first time, a cancer treatment has been approved for any solid tumor, irrespective of the tumor’s …
First cancer treatment for any solid tumor with MSI-H or dMMR approved Read more »
May 18, 2017 – Ivacaftor (Kalydeco) is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator indicated for the treatment of cystic fibrosis (CF) in patients age 2 years and older who are carriers one of the following mutations in the CFTR gene: …
September 17, 2016 – Breast cancer is the most common cancer in women worldwide, with nearly 1.7 million new cases diagnosed in 2012. In Europe, there were an estimated 464,000 new cases of breast cancer in 2012 and an estimated 131,000 …
Palbociclib (Ibrance): New treatment for advanced or metastatic breast cancer in the EU Read more »
July 26, 2016 – Renal cell carcinoma is the most common form of kidney cancer in adults. Advanced renal cell carcinoma includes both metastatic disease and locally advanced renal cell carcinoma that cannot be removed by surgery. Despite the recent …
Cabometyx and Kisplyx: Two new medicines for advanced kidney cancer Read more »
May 28, 2016 – Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune disease of the central nervous system that disrupts communication between the brain and other parts of the body. It is among the most common causes of neurological disability in …
Daclizumab (Zinbryta) approved for the treatment of multiple sclerosis (MS) Read more »
May 17, 2016 – Do targeted therapies diminish market volumes? Not necessarily, as we can nicely learn from the example of Nivolumab (Opdivo). While initially the targeted development of a drug (Nivolumob (Opdivo) in this case) may lead to a somewhat restricted …
Nivolumab (Opdivo): Do targeted therapies diminish market volumes of drugs? Read more »
February 26, 2016 – Two new treatments for oncologic indications have been approved by the American Food and Drug Administration (FDA). Thus, the FDA approved Obinutuzumab (Gazyva) for use in combination with bendamustine followed by Obinutuzumab (Gazyva) monotherapy for the treatment of patients with follicular …
News for Obinutuzumab (Gazyva) and Everolimus (Afinitor) Read more »