October 21, 2022 – Why we want to drink (possibly too much)? And what has that to do with our genes, and why it matters for our alcohol risk? These are some of the question coming out of a recent …

Why we want to drink: Are there genes behind it? Read more »

October 14, 2022 – “Gambia Police Link Child Deaths to Cough Syrups Imported by US Firm”. This is a report from Reuters that illustrates in a tragic fashion the problem of globalisation of all processes involved in providing medicines to the needing …

The Gambia: Childrens deaths due to cough syrups Read more »

September 25, 2022 – Nearly 2000 years ago the Roman scholar and natural philosopher Pliny the Elder wrote in his Natural History: “Ex Africa surgit semper aliquid novi” (from Africa there is always something new). This quote beautifully applies to …

Genetic studies of African populations on disease susceptibility and response to vaccines and therapeutics  Read more »

September 21, 2022 – Here, a big bias in genetic research into its applicability on “personalized”, or “precision”, or “theragenomic” medicine is finally addressed and brought forward to all involved in these fields. The problem until now is (and was} that …

Ethnic equity in precision medicine Read more »

September 16, 2022 – Beta thalassemias (β thalassemias) are a group of inherited blood disorders. They are forms of thalassemia caused by reduced or absent synthesis of the beta chains of hemoglobin that result in variable outcomes ranging from severe anemia …

Gene therapy: Hope for patients with beta-thalassemia? Read more »

September 03, 2022 – Sometimes, in sleepless nights, as an ever and never stopping inquiring mind, you may stumble over just flabbergastingly mind-boggling stuff like this. The issue is “doppelgänger” and the possible genetic similarities behind it. Doppelgänger means people that …

My doppelgänger: Has he/she my DNA and my genes too? Read more »

August 26, 2022 – Traditionally, pharmacovigilance (PV), is the pharmaceutical science relating to the “collection, detection, assessment, monitoring, and prevention” of adverse drug reactions (ADRs) with pharmaceutical products and associated therapies. Pharmacovigilance is based on information about ADRs received from patients and healthcare …

Pharmacogenovigilance: Has the time come? Read more »

August 21, 2022 – Systemic lupus erythematosus (SLE) is a common, incurable autoimmune disease that affects millions of individuals worldwide, with a particularly high prevalence among women. A genetic variant, called HLA-DRB1*03:01, is the greatest risk factor for the condition, …

Serious lupus: Strong genetic risk factor on its path Read more »

August 18, 2022 – The question why certain patients suffer from very severe, even fatal conditions after infections with SARS-CoV-2 has occupied patients, the general population, medical professionals, and the media all alike for some time now. As a basic researcher …

Do genomic regions influence the severity of Covid-19 disease? Read more »

August 13, 2022 – Breast cancer: Is BIA-ALCL increasing in women in the US? Over the last couple of years, the recognition of an seemingly increased rate of incidence of Anaplastic Large-Cell Lymphoma (ALCL) in woman who received breast implants …

Breast cancer: Is BIA-ALCL increasing in women in the US? Read more »