Last Updated on September 18, 2016 by Joseph Gut – thasso  September 17, 2016 – Breast cancer is the most common cancer in women worldwide, with nearly 1.7 million new cases diagnosed in 2012. In Europe, there were an estimated 464,000 …

Palbociclib (Ibrance): New treatment for advanced or metastatic breast cancer in the EU Read more »

Last Updated on September 9, 2016 by Joseph Gut – thasso September 09.  2016 – The pre-clinical animal model and Phase 1b placebo-controlled study in prodromal and mild Alzheimer Disease (AD) patients (n=165), both demonstrate that aducanumab reduced amyloid-beta in …

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease Read more »

Last Updated on September 8, 2016 by Joseph Gut – thasso September 08, 2016 – Ovarian cancer occurs when abnormal cells in or near the ovaries grow and form a malignant (cancerous) tumor. In the United States, ovarian cancer is the …

FDA recommends against use of ovarian cancer screening tests Read more »

Last Updated on September 7, 2016 by Joseph Gut – thasso September 06, 2016 – Apple has updated it’s App Store guidelines on health and medical Apps. Developers of health and medical apps will now have strict rules to abide by …

Apple App Store guidelines tightened for health and medical apps Read more »

Last Updated on September 6, 2016 by Joseph Gut – thasso September 06, 2016 – Genetic mutations associated with acquired resistance to PD-1 blockade in melanoma have been suspected to be involved in the clinical observation that while approximately 75% of …

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma Read more »

Last Updated on September 4, 2016 by Joseph Gut – thasso September 04, 2016 – Case Comprehensive Cancer Center researchers, a research collaboration which includes University Hospitals Seidman Cancer Center and Case Western Reserve University, who last year identified new gene …

Adverse clinical outcome associated with mutations in colorectal cancers of African Americans Read more »

Last Updated on September 3, 2016 by Joseph Gut – thasso September 03, 2016 – This morning, I stumbled upon the headline of a posting on mobihealthnews, entitled “Study finds iPads and games as effective as sedatives to calm pre-op …

Is the iPad a medical device? Read more »

Last Updated on October 12, 2016 by Joseph Gut – thasso September 01, 2016 – This is what we learned this morning and sadly, the issue of opioids use in the population along with its fatal outcomes seems never to stop. …

The opioid epidemic: Is there a never ending sad story? Read more »

Last Updated on August 30, 2016 by Joseph Gut – thasso August 30, 2016 – The present article which just appeared in August 2016 issue of  PLOS Medicine illustrates how the inaccurate and biased to say the least the assessment …

Orlistat: Assessment of Adverse Events in Protocols, Clinical Study Reports, and Published Papers Read more »

Last Updated on August 26, 2016 by Joseph Gut – thasso August 26, 2016 – Eltrombopag is a medication that has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts). It is a small molecule agonist of the c-mpl (TpoR) receptor, which is the physiological target of the hormone thrombopoietin. Eltrombopag …

Eltrombopag (Revolade) can cause severe hepatotoxicity and potentially fatal liver injury Read more »