the glocalized network in theragenomic and personalized medicine and the genetics of individual patients safety of drugs
October 21, 2017 – Just seen on PubMed: Ziegelstein RC J Pers Med 2017 Oct;7(4) PMID: 29035320 Abstract Clinical practice guidelines have been developed for many common conditions based on data from randomized controlled trials. When medicine is informed …
Personomics: The Missing Link from Precision Medicine to Personalized Medicine Read more »
June 30, 2017 – The below citation from PubMed addresses an vey important issue associated with genetic testing in theragenomic and personalized medicine. It is the question if the genetic test used to stage, classify, or determine treatability of a …
March 06, 2017 – The following article by Samet et. al. discusses the impact that newly sought after legislation and budgeting cuts by the Trump Administration may have on environmental health. Usually, thasso post does not address politically based issues; …
The Trump Administration and the environment: Impact on human health Read more »
March 2, 2017 – This post is about the health risks associated with recreational use of Cannabis and all the aspects that come along with its legalization in at least some states in the United States. The post simply reproduces …
Hot topic: Minimizing the health risks from legalization of Cannabis Read more »
October 11, 2016 – Here, you will find an overview article on applied epigenetics and its role when it comes to cancer. This is heavy material to read and therefore most probably geared toward the science-inclined readers of thasso post …
Epigenetics in Cancer: A Hematological Perspective Read more »
September 09. 2016 – The pre-clinical animal model and Phase 1b placebo-controlled study in prodromal and mild Alzheimer Disease (AD) patients (n=165), both demonstrate that aducanumab reduced amyloid-beta in the brain and the reduction was dose-dependent. Amyloid-beta plaque is associated …
The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease Read more »
September 04, 2016 – Case Comprehensive Cancer Center researchers, a research collaboration which includes University Hospitals Seidman Cancer Center and Case Western Reserve University, who last year identified new gene mutations unique to colon cancers in African Americans, have found that …
August 30, 2016 – The present article which just appeared in August 2016 issue of PLOS Medicine illustrates how the inaccurate and biased to say the least the assessment and the reporting of adverse drug reactions by pharmaceutical companies throughout …
Sacco K, Grech G EPMA J 2015;6(1):15 PMID: 26203310 Abstract Breast cancer is a heterogeneous disease that necessitates proper patient classification to direct surgery, pharmacotherapy, and radiotherapy. Despite patients within the same subgroup receiving similar pharmacotherapy, substantial variation in clinical …
Actionable pharmacogenetic markers for prediction and prognosis in breast cancer Read more »
August 14, 2016 – The PubMed-article below illustrates how pharmacogenetics and/or pharmacogenomics-guided drug therapy (i.e., theragenomic medicine) has its place and impact on patients and healthcare systems in African countries when it comes to large disease burdens such as in …