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Your genes and your opioids: Pain relief or addiction? Or both?

March 14, 2019 – Genetic predisposition may help to explain opioid based pain relief, addiction, or the combination of both. In a perfect world, and in battling the rampant opioid crises in the US and other parts of the world, doctors would be able to identify those patients who are prone to opioid addiction and prescribe them non-opioid painkillers that wouldn’t lead to dependence.

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The opioid epidemic: Is there a never ending sad story?

September 01, 2016 – This is what we learned this morning and sadly, the issue of opioids use in the population along with its fatal outcomes seems never to stop.  The American Food & Drug Asministation (FDA) requires, according to a press release this morning,

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Opioids and their related risks of misuse, abuse, addiction, overdose and death: FDA announces enhanced warnings for immediate-release opioid pain medications

March 23, 2016 –  The present announcement by the American Food and Drug Administration (FDA) needs no further commentary and is reprinted here without editing as follows:
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In a continuing effort to educate prescribers and patients about the potential risks related to opioid use,

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  • Genes, the social environment, and adolescent smoking September 17, 2019
    Adolescence is a time of dramatic change. It marks a period of significant physical transformation—such as the drive toward sexual maturity. But it can also be a time of considerable psychological change and social experimentation.
  • Cause of rare, fatal disorder in young children pinpointed September 17, 2019
    Scientists at Washington University School of Medicine in St. Louis appear to have solved a decades-long mystery regarding the precise biochemical pathway leading to a fatal genetic disorder in children that results in seizures, developmental regression and death, usually around age 3. Studying a mouse model with the same human illness—called Krabbe disease—the researchers also […]
  • Gene-targeted cancer drugs, slow release overcome resistance September 16, 2019
    Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve the efficacy, accuracy and longevity of certain cancer therapies.
  • Genetic mutation appears to protect some people from deadly MRSA September 16, 2019
    An inherited genetic tendency appears to increase the likelihood that a person can successfully fight off antibiotic-resistant staph infections, according to a study led by Duke Health researchers.
  • Renegade genes caught red handed September 16, 2019
    The guardians of the human genome that work to prevent potentially disease-causing gene expression might not be as effective at their jobs as previously thought, according to new University of Arizona research.
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