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Nicht so gut: Erhöhtes Risiko für Amputationen der unteren Extremitäten mit SGLT2-Inhibitoren

11. Februar 2017 – Nicht so gut, diese Nachricht für Diabetes-Patientinnen und -Patienten. Der Ausschuss für Risikobewertung im Bereich der Pharmakovigilanz (PRAC) bei der Europäischen Arzneimittel-Agentur (EMA) warnt, dass in zwei klinischen Prüfungen, CANVAS und CANVAS-R, eine größere Anzahl von Amputationen der unteren Extremitäten (vorwiegend der Zehen) bei Patienten beobachtet worden ist,

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SGLT2-Hemmer: Empfehlung des PRAC zur Minimierung des Risikos von diabetischen Ketoazidosen

15. Februar 2016 – Die folgende Mittteilung stammt vom Deutschen Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM). Die Mitteilung ist mit minimalem Editieren durch den Author des Blogs wiedergegeben. Here we go:

Der Ausschuss für Risikobewertung der Europäischen Arzneimittelagentur (PRAC) hat das europäische Risikobewertungsverfahren zu SGLT2-Inhibitoren (eine Klasse von Arzneimitteln zur Behandlung von Typ-2-Diabetes) beendet und Empfehlungen zur Minimierung des Risikos von diabetischen Ketoazidosen ausgesprochen.

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