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Fatal Adverse Events with Pazopanib [Votrient], Sorafenib [Nexavar], and Sunitinib [Sutent]

February 12, 2012 – From an article published in Medscape Oncology News on February 9, 2012, we learn the following (article in full, all rights resting with Medscape Oncology News):

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February 9, 2012— New details on the risk for fatal adverse events associated with several targeted cancer drugs have come from a large meta-analysis of clinical trials,

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Sunitinib [Sutent] und Bevacizumab [Avastin]: Kiefer-Osteonekrosen bei gleichzeitiger oder früherer Therapie mit Bisphosphonat-haltigen Arzneimitteln

24. Dezember 2010 – Swissmedic macht uns folgende Information zugänglich (Text durch den Blog-Author leicht adaptiert):

Die beiden Präparate Sunitinib [Sutent] und Bevacizumab [Avastin] sind für die Behandlung bestimmter fortgeschrittener Krebserkrankungen zugelassen und haben Wirkungen auf die Tumor-Gefässbildung und damit auf die Versorgung des Tumorgewebes mit Nährstoffen und Sauerstoff.

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