November 02, 2024 – In the popular press and with people of public interest and fame in the weightloss and beauty industries, Semaglutide has been considered the slimming miracle elixir par excellence. Wegovy, Rybelsus, and Ozempic, all of which are based on …

Semagludite: The cause for NAION and Blood Clots? Read more »

January 26, 2021 – To date, a rare serious adverse (drug) reaction (SADR) has been noted to be associated with the first two Covid-19 vaccines, i.e., the one from Pfizer-BioNTech and the one from Moderna. We are talking about anaphylaxis, which …

Rare cases of anaphylaxis with COVID-19 vaccines Read more »

December 28, 2020 – Some 95% of people have gene variants that may negatively affect their response to at least one drug, leading to unexpected or adverse drug reactions (ADRs) or, if unlucky, to a serious, if not fatal, adverse …

Genetics behind some serious adverse drug reactions (SADRs) Read more »

September 30, 2017 – Obeticholic acid (Ocaliva) was approved by the American Food & Drug Administration (FDA) in May 2016 for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adult  patients with an inadequate response …

Obeticholic Acid (Ocaliva): Is there a serious drug safety problem? Read more »

May 17, 2017 – Following up on an earlier Drug Safety Communication from May 2016 and based on new data from two large clinical trials, the American Food & Drug Administration (FDA) has concluded that the type 2 diabetes medicines …

Risk of leg and foot amputations under Canagliflozin (Invokana, Invokamet) Read more »

May 11, 2016 – We do learn from a very recent Drug Safety Communication (DSC) by the American Food & Drug Administration (FDA) that olanzapine, the pharmacologically active component in Zyprexa, Zyprexa Zydis, Zyprexa Relprevv, Symbyax, and olanzapine generics may cause …

DRESS: Rare but serious skin reaction with Zyprexa (Olanzapine) Read more »