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Tag: Prodrug

FDA Drug Safety Communication: Reduced effectiveness of Clopidogrel [Plavix] in patients who are poor metabolizers (i.e. carriers of selected CYP2C19 allelic variants) of the drug

By Joseph Gut - thasso Posted on March 17, 2010 Posted in Efficacy, Personalized Medicine, Pharmacogenetics Tagged with Allelic Variants, Clopidogrel [Plavix], CYP2C19, CYP2C19*2, CYP2C19*3, Genetic Testing, Personalized Medicine, Pharmacogenetics, Poor Metabolizer, Prodrug

March 17, 2010 – The U.S. Food and Drug Administration (FDA) has added a Boxed Warning to the label for Clopidogrel [Plavix], the anti-blood clotting medication. The Boxed Warning is about patients who do not effectively metabolize the drug (i.e. …

FDA Drug Safety Communication: Reduced effectiveness of Clopidogrel [Plavix] in patients who are poor metabolizers (i.e. carriers of selected CYP2C19 allelic variants) of the drug Read more »

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