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Progressive Multifokale Leukoenzephalopathie (PML): Seltene Fälle nach Behandlung von MS-Patienten mit Fingolimod (Gilenya)

11 Juni 2016 – In Abstimmung mit Swissmedic, dem Schweizerischen Heilmittelinstitut, hat Novartis Pharma über das Auftreten in der Vergangenheit  von vereinzelten Fälle von progressiver multifokaler Leukoenzephalopathie (PML) bei Patienten mit schubförmig remittierend verlaufender Multipler Sklerose (MS) nach Behandlung mit Fingolimod (Gilenya) informiert.

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Fulminante Lebertoxizität mit tödlichem Verlauf unter Zynbryta (Daclizumab)

 21. Juli 2017 – Aus einer Mitteilung der Arzneimittelkommission der Deutschen Ärzteschaft (Drug Safety Mail 2017-24 vom 17. Juli 2017) geht hervor, dass in einigen Patienten / Patientinnen unter Behandlung mit Zynbryta (Daclizumab) fulminante Lebertoxizitäten mit tödlichem Verlauf auftreten können.

Zynbryta (Daclizumab) ist ein humanisierter monoklonaler Antikörper gegen den Interleukin-2-Rezeptor (genauer: gegen die α-Kette CD25),

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  • Nurse practitioners play key role in opioid addiction treatment in very rural areas November 23, 2020
    Giving nurse practitioners the authority to prescribe buprenorphine has brought that gold standard treatment for opioid addiction to people who might not have had access to it before, according to a new study. Looking at prescription drug monitoring data in Oregon before and after 2017, when nurse practitioners and physician assistants gained the authority to […]
  • Identical evolution of isolated organisms November 23, 2020
    Palaeontologists at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and the University of Calgary in Canada have provided new proof of parallel evolution: conodonts, early vertebrates from the Permian period, adapted to new habitats in almost identical ways despite living in different geographical regions. The researchers were able to prove that this was the case using fossil teeth found […]
  • A chemist from RUDN University synthesized analogs of natural toxins November 23, 2020
    A chemist from RUDN University suggested a simple and accurate method for the synthesis of analogs of two natural toxins, antofine and septicine. This universal approach can also be used to obtain other biologically active substances for medicinal chemistry.
  • Researchers minimize quantum backaction in thermodynamic systems via entangled measurement November 23, 2020
    Researchers from University of Science and Technology of China theoretically proved that the backaction can be suppressed to zero in a two qubit system, and conducted the first experiment using entangled collective measurement for minimizing quantum measurement backaction based on photonic system.
  • Growing risks of STIs in over-45s November 23, 2020
    Sexually-active over-45s are at a high risk of contracting STIs because people do not want to talk about holder people having sex, a report has found.