Blog Archives

Granpidam: A generic to Sildenafil (Revatio)

September 22, 2016 – The pharmacologically active compound known as sildenafil is largely used to treat erectile dysfunction (on the market for this indication under the trade name Viagra) and pulmonary arterial hypertension (on the market for this indication under the trade name Revatio) in the United

States (US),

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SGLT2 inhibitors and diabetic ketoacidosis: PRAC makes recommendations to minimise risk to patients

February 14, 2016 – Diabetic ketoacidosis is a serious complication of diabetes caused by low insulin levels. Rare cases of this condition, including life-threatening ones, have occurred in patients taking SGLT2 inhibitors for type 2 diabetes and a number of these cases have been atypical,

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Osimertinib (Tagrissa) approved for non-smal cell lung cancer (NSCLC) patient subgroup carrying the EGFR T790M mutation

February 07, 2016 – The European Commission has approved once-daily Osimertinib (Tagrissa) for the treatment of patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC) that is positive for the epidermal growth-factor receptor (EGFR) T790M mutation. This follows a positive review in December 2015.

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Is there help for patients suffering from gout? Lesinurad (Zurampic) approved for the treatment of high blood uric acid levels

December 24, 2015 – The American Food and Drug Administration (FDA) just approved Lesinurad  (Zurampic) to treat high levels of uric acid in the blood (hyperuricemia) associated with gout, when used in combination with a xanthine oxidase inhibitor (XOI),

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CHMP recommended Harvoni [Ledipasvir / Sofosbuvir] for the treatment of chronic hepatitis C

October 10, 2014 – The European Medicines Agency recently has recommended the authorisation of Harvoni (ledipasvir / sofosbuvir) for the treatment of chronic hepatitis C virus (HCV) infection in adults. HCV infection is a major European public-health challenge. It affects between 0.4% and 3.5% of the population in different European Union (EU) Member States and is the most common single cause of liver transplantation in the EU.

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EMA: EU Panel Endorses Daclatasvir (Daklinza) for Chronic Hepatitis C Infection

July 10, 2014 – The European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) has endorsed daclatasvir (Daklinza, Bristol-Myers Squibb) to treat adults with chronic hepatitis C virus (HCV) infection, in combination with other drugs.

Daclatasvir is the first in a new class of antivirals that block the action of NS5A,

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  • Study explores cognitive function in people with mental illness January 22, 2020
    A study funded by the Veterans Administration and directed by researchers at the University of Miami Miller School of Medicine has shown few differences in the profiles of genes that influence cognition between people with schizophrenia, bipolar disorder and the general population. This surprising finding could provide new insights into therapies designed to improve cognition. […]
  • Hope for patients with a rare genetic condition linked to severe infections January 22, 2020
    A team of researchers at CHU Sainte-Justine and Université de Montréal has shed light on the mechanisms that underlie a rare genetic condition by creating the first cellular model of the disease. The study's findings were published today in the Journal of Allergy and Clinical Immunology.
  • Avatar worms help to identify factors that modify genetic diseases January 21, 2020
    Often, patients from the same family and carriers of the same genetic mutation, develop a disease differently. This disparity may be due to the existence of mutations in other secondary genes, which influence the onset and progression of the disease caused by the main mutation. As an example, members of a family who are carriers […]
  • Algorithm turns cancer gene discovery on its head January 21, 2020
    A method for finding genes that spur tumor growth takes advantage of machine learning algorithms to sift through reams of molecular data collected from studies of cancer cell lines, mouse models and human patients.
  • Blood test for eight gene signatures could predict onset of tuberculosis January 21, 2020
    Scientists at UCL have shown a blood test could predict the onset of tuberculosis three to six months before people become unwell, a finding which could help better target antibiotics and save countless lives.
  • Obesity embargo alert for February 2020 issue January 23, 2020
    All print, broadcast and online journalists who receive the Obesity embargo alert agree to abide by the embargo and may not publish, post, broadcast or distribute embargoed news releases or details of the embargoed studies before the embargo date and time.
  • How old are they? Some non-photosynthetic orchids consist of dead wood January 23, 2020
    A research team led by Kobe University's Associate Professor SUETSUGU Kenji (of the Graduate School of Science's Department of Biology) has investigated the carbon age in some non-photosynthetic mycoheterotrophic plants. Using the radiocarbon emitted from atmospheric nuclear bomb tests carried out in the 1950s and 1960s as a tracer, they revealed that some mycoheterotrophic orchids […]
  • Most rehabilitating sea turtles with infectious tumors don't survive January 22, 2020
    Fibropapillomatosis (FP) is the most significant infectious disease affecting sea turtle populations worldwide. FB leads to tumors on the turtles' eyes, flippers and internal organs and is widespread in warmer climates like Florida. A large-scale study evaluated tumor score, removal and regrowth in rehabilitating green sea turtles with FP in the southeastern US from 2009 […]
  • Tiny price gaps cost investors billions January 22, 2020
    New research shows that, millions of times each day, investors in the US stock market see different prices at the same moment -- and that these differing prices cost investors at least $2 billion dollars each year.
  • Kids born to moms with gestational diabetes and preeclampsia at greater risk for obesity January 22, 2020
    A study in Archives of Gynecology and Obstetrics found that when a mother experiences both gestational diabetes and preeclampsia, her child has a growth trajectory that leads to an increased risk of high childhood BMI over time.
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