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This is it: First blood test to detect EGFR gene mutations in NSCLC

June 03, 2016 – This is a huge step in the application of theragenomic medicine in cancer patients in the quest to deliver highly individualized health care for patients. Thus, on June 01, the American Food & Drug Administration (FDA) approved the cobas EGFR Mutation Test v2,

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FDA Approves Companion Genetic Diagnostic Test for Erlotinib [Tarceva] in NSCLC

May 14, 2013 – The US Food and Drug Administration (FDA) today announced the approval of the cobas EGFR Mutation Test, a companion diagnostic for the cancer drug Erlotinib (Tarceva). This is the first FDA-approved companion diagnostic that can detect epidermal growth factor receptor (EGFR) gene mutations,

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  • New CRISPR advance may solve key quandary June 2, 2020
    A mutation unique to certain cancer tumors is a potential homing beacon for safely deploying CRISPR gene editing enzymes to disarm DNA that makes cancer cells resistant to treatment, while ignoring the gene in normal cells where it's critical to healthy function, according to a new study from ChristianaCare's Gene Editing Institute in the journal […]
  • Gene discovery in fruit flies 'opens new doors' for hearing loss cure in elderly June 2, 2020
    Scientists at UCL have discovered sets of regulatory genes, which are responsible for maintaining healthy hearing. The finding, made in fruit flies, could potentially lead to treatments for age-related hearing loss (ARHL) in humans.
  • Study reveals how a master regulator of gene transcription operates June 2, 2020
    Using targeted protein degradation technology, researchers at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, set out to understand the primary role of a key regulator of transcription, the human Mediator complex. Mediator, a 30-subunit molecular machine, was believed to be a factor that is generally required for the transcription […]
  • Genetic cause of difference in sexual development uncovered June 1, 2020
    Researchers at the Francis Crick Institute, the Institut Pasteur and their clinical collaborators have identified a cause of testicular tissue developing in people with female chromosomes.
  • The interface of genomic information with the electronic health record June 1, 2020
    Advances in genetic and genomic testing technology have not only introduced the utilization of clinical genomic information into virtually every area of medical care, this testing has become an essential tool to achieve the goal of precision medicine. As genomic data become more complex, so too must the electronic health record (EHR) evolve to provide […]
  • Piecing together the Dead Sea Scrolls with DNA evidence June 2, 2020
    Piecing together the collection of more than 25,000 fragments of ancient manuscripts known as the Dead Sea Scrolls in order to understand their meaning has remained an incredibly difficult puzzle. Now, researchers reporting in the journal Cell on June 2 have used an intriguing clue to help in this effort: DNA "fingerprints" lifted from the […]
  • Bees grooming each other can boost colony immunity June 2, 2020
    Honeybees that specialise in grooming their nestmates (allogroomers) to ward off pests play a central role in the colony, finds a new UCL and University of Florence study published in Scientific Reports.
  • Extracellular vesicles play an important role in the pathology of malaria vivax June 2, 2020
    Extracellular vesicles (EVs) play a role in the pathogenesis of malaria vivax, according to a study led by researchers from the Barcelona Institute for Global Health (ISGlobal) and the Germans Trias i Pujol Health Science Research Institute (IGTP). The findings, published in Nature Communications, indicate that EVs from P. vivax patients communicate with spleen fibroblasts […]
  • When determining sex, exceptions are the rule June 2, 2020
    Thanks to new genomic data, long-held theories on sex chromosome evolution are now being tested against empirical evidence from nature -- often with surprising results.
  • Carnegie Mellon tool automatically turns math into pictures June 2, 2020
    Some people look at an equation and see a bunch of numbers and symbols; others see beauty. Thanks to a new tool created at Carnegie Mellon University, anyone can now translate the abstractions of mathematics into beautiful and instructive illustrations. The tool enables users to create diagrams simply by typing an ordinary mathematical expression and […]
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