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Wer kennt Duogynon (Norethisteron)? Eine dunkle Geschichte

10. Dezember 2016 – Wenn langsam der Winter ins Land zieht und weihnächtliche Romantik selbst in hochprofessionelle Arbeitswelten modernster Ausgestaltung Einzug hält, ertappt sich der Author dieses imageBlogs dabei, nostalgisch zu werden und hie und da geudanklich in die anscheinend bessere Vergangenheit abzuschweifen. Interessanterweise stösst man dabei in den dunklen Monaten nicht selten auch auf eher dunkle Geschichten.

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Virus-Reaktivierung und pulmonale Hypertonie unter Therapie mit Thalidomide Celgene

23. Juni 2016 – Mittels eines Rote-Hand-Briefes informiert die Firma Celgene in Deutschland darüber, dass bei Patienten unter Thalidomide Celgene Therapie Fälle von Virus-Reaktivierung aufgetreten sind, darunter schwerwiegende Fälle, insbesondere bei Patienten, die sich zuvor mit Herpes Zoster oder Hepatitis-B-Virus (HBV)

infiziert hatten.

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  • Twenty four genetic variants linked to heightened womb cancer risk February 17, 2020
    Twenty four common variations in genes coding for cell growth and death, the processing of oestrogen, and gene control factors may be linked to a heightened risk of developing womb (endometrial) cancer, indicates the most comprehensive review of the published evidence so far in the Journal of Medical Genetics.
  • Researchers discover the link between ribs and lung function in patients with brittle bone disease February 17, 2020
    A multidisciplinary team headed by Valencia University (UV) professor Juan Alberto Sanchis Gimeno reports on the link between the shape of the ribs and lung function in patients with osteogenesis imperfecta, a rare disease that affects one of every 18,000 newborns. Their study has been published in the Journal of Advanced Research.
  • Key modifier found in genetic deletion related to neurodevelopmental disorders February 14, 2020
    Neurodevelopmental disorders, including schizophrenia and autism, likely result from complex interactions that modify the effects of individual genes. In a new study, researchers evaluated the effects of over 300 pairwise knockdowns—reducing the expression of two genes simultaneously—of the fruit fly versions of genes located in a region of human chromosome 3 that, when deleted, has […]
  • Stress in small children separated from their parents may alter genes February 14, 2020
    Experts in the emotional needs of small children say increased levels of the stress hormone cortisol in babies and small children who are separated from their parents, especially their mothers, could have a long-term genetic impact on future generations. In a commentary published by the Journal of the Royal Society of Medicine, the authors say […]
  • Autophagy genes act as tumor suppressors in ovarian cancer February 13, 2020
    Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina (MUSC) and University of California at San Diego (UCSD) published findings in PLOS Genetics this month showing that autophagy or "self-eating" genes work against tumors in certain types of ovarian cancer.