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Information über potentielle Wechselwirkungen von Protonen-Pumpen-Inhibitoren (PPI’s) mit Clopidogrel-haltigen Arzneimitteln

7. Dezember 2009 – Sanofi Pharma Bristol-Myers Squibb informiert in Übereinstimmung mit dem Deutschen Bundesinstitut für Arzneimittel und Medizinalprodukte (BfArM) darüber, dass die Europäische Fachinformation (Summary of Product Characteristics, SPC) für Clopidogrel-Hydrogensulfat, in Verkehr gebracht als Plavix®, überarbeitet worden ist.

Danach wird in die SPC ein Warnhinweis aufgenommen,

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Clopidogrel-haltige Arzneimittel (Plavix®, Iscover®): potentielle Wechselwirkungen mit Protonen-Pumpen-Inhibitoren (PPIs)

6. August 2009 – In einer Mitteilung vom 4. August 2009 bittet das Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) um dringende Beachtung der aktualisierten Warnhinweise und Vorsichtsmaßnahmen in der Fachinformation zu Clopidogrel [Plavix] und Clopidogrel [Iscover]. Zu den Änderungen werden Rote-Hand-Briefe versendet. Hier folgend finden sie den leicht editierten und gekürzten Inhalt des Rote Hand Briefes für Plavix®.

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  • Tick, tock: How stress speeds up your chromosomes' aging clock December 5, 2019
    Ageing is an inevitability for all living organisms, and although we still don't know exactly why our bodies gradually grow ever more decrepit, we are starting to grasp how it happens.
  • Genome testing for siblings of kids with autism may detect ASD before symptoms appear December 5, 2019
    One of the key priorities of interventions for autism spectrum disorder (ASD) is starting early, with some evidence showing infants as young as seven months old could benefit. Yet, most children in North America aren't diagnosed with ASD until they're over four years of age. New research led by The Hospital for Sick Children (SickKids) […]
  • 2019: the year gene therapy came of age December 5, 2019
    In the summer, a mother in Nashville with a seemingly incurable genetic disorder finally found an end to her suffering—by editing her genome.
  • Scientists create 'epigenetic couch potato' mouse December 4, 2019
    Why is it that some people love to exercise, and others hate it? Most people would assume it's all due to genetics, but a new Baylor College of Medicine led study in mice shows for the first time that a different molecular level of regulation—epigenetics—plays a key role in determining one's innate drive to exercise. […]
  • Human genetic enhancement might soon be possible—but where do we draw the line? December 4, 2019
    The first genetically edited children were born in China in late 2018. Twins Lulu and Nana had a particular gene—known as CCR5—modified during embryonic development. The aim was to make them (and their descendants) resistant to HIV. By some definitions, this would be an example of human enhancement.
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