Luxturna contre la cécité vendu 850 000 dollars

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o4 janvier 2018 – Aux États-Unis, le médicament contre une dégénérescence rétinienne rare et héréditaire pouvant évoluer vers la cécité totale, le Luxturna sera vendu 850.000 dollars (425.000 dollars par oeil). Le prix final reste en dessous d’un million de dollars initialement évoqué mi-décembre lorsque son fabricant, la société de biotechnologies Spark Therapeutics, avait reçu l’autorisation de

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mise sur le marché de l’agence américaine du médicament (FDA). Le laboratoire a promis de rembourser les malades si le traitement n’était pas efficace et envisage également de demander aux autorités sanitaires d’autoriser un paiement par étape.

Outre Luxturna, d’autres traitements avoisinent le million de dollars actuellement (parfois en lien avec le fait qu’ils nécessitent de recourir à plusieurs doses). C’est le cas de Spinraza (Nusinersen en Europe), développé par Biogen et Ionis Pharmaceuticals contre l’atrophie musculaire, et de Soliris, fabriqué par Alexion Pharmaceuticals pour traiter une maladie rare des reins. Ils coûtent tous les deux environ 750.000 dollars. La palme du médicament le plus cher au monde revient toutefois à Glybera, premier médicament génique vendu un million de dollars par le groupe néerlandais UniQure pour soigner plusieurs maladies génétiques. Le Luxturna s’inspire ainsi d’une démarche adoptée récemment par le laboratoire suisse Novartis lors du début de la commercialisation de Kymriah, censé traiter une forme très agressive de leucémie chez des enfants et de jeunes adultes. Le laboratoire suisse s’est engagé à rendre l’argent aux assureurs et malades en cas d’inefficacité de cet autre traitement, vendu 475.000 dollars.

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Joseph Gut - thasso Professeur de pharmacologie et de toxicologie. Expert en médecine théragenomique et personnalisé el le sécurité individualisé des médicaments. Expert dans pharmaco- et toxico-génétique. Expert en matière de sécurité humaine de médicaments, les produits chimiques, les polluants environnementaux, et des ingrédients alimentaires.

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